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Highly reactive “RIKEN click” probe for glycoconjugation on lysines
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| dc.contributor.author | Sibgatullina R. | |
| dc.contributor.author | Fujiki K. | |
| dc.contributor.author | Murase T. | |
| dc.contributor.author | Yamamoto T. | |
| dc.contributor.author | Shimoda T. | |
| dc.contributor.author | Kurbangalieva A. | |
| dc.contributor.author | Tanaka K. | |
| dc.date.accessioned | 2018-09-19T22:00:10Z | |
| dc.date.available | 2018-09-19T22:00:10Z | |
| dc.date.issued | 2017 | |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/144576 | |
| dc.description.abstract | © 2017 Elsevier LtdOne pot double click strategy containing strain-promoted click-reaction followed by 6π-azaelectrocyclization (RIKEN click reaction) has worked well in the synthesis of multivalent homogeneous and heterogeneous N-glycoalbumins. We have slightly changed the structure of linker unsaturated aldehyde used in this method. As a result it can be easily synthesized from commercially available material and furthermore, the enhancement of its reactivity towards both click-reactions was observed. The data described in this Communications facilitate the usage of the double click strategy as a general method for the synthesis of a variety of neo-N-glycoproteins. | |
| dc.relation.ispartofseries | Tetrahedron Letters | |
| dc.subject | Asparagine-linked glycans (N-glycans) | |
| dc.subject | Glycoconjugation | |
| dc.subject | Lysine | |
| dc.subject | N-Glycoalbumin | |
| dc.subject | RIKEN click reaction | |
| dc.title | Highly reactive “RIKEN click” probe for glycoconjugation on lysines | |
| dc.type | Article | |
| dc.relation.ispartofseries-issue | 20 | |
| dc.relation.ispartofseries-volume | 58 | |
| dc.collection | Публикации сотрудников КФУ | |
| dc.relation.startpage | 1929 | |
| dc.source.id | SCOPUS00404039-2017-58-20-SID85017559448 |
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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.