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Highly reactive “RIKEN click” probe for glycoconjugation on lysines

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dc.contributor.author Sibgatullina R.
dc.contributor.author Fujiki K.
dc.contributor.author Murase T.
dc.contributor.author Yamamoto T.
dc.contributor.author Shimoda T.
dc.contributor.author Kurbangalieva A.
dc.contributor.author Tanaka K.
dc.date.accessioned 2018-09-19T22:00:10Z
dc.date.available 2018-09-19T22:00:10Z
dc.date.issued 2017
dc.identifier.issn 0040-4039
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/144576
dc.description.abstract © 2017 Elsevier LtdOne pot double click strategy containing strain-promoted click-reaction followed by 6π-azaelectrocyclization (RIKEN click reaction) has worked well in the synthesis of multivalent homogeneous and heterogeneous N-glycoalbumins. We have slightly changed the structure of linker unsaturated aldehyde used in this method. As a result it can be easily synthesized from commercially available material and furthermore, the enhancement of its reactivity towards both click-reactions was observed. The data described in this Communications facilitate the usage of the double click strategy as a general method for the synthesis of a variety of neo-N-glycoproteins.
dc.relation.ispartofseries Tetrahedron Letters
dc.subject Asparagine-linked glycans (N-glycans)
dc.subject Glycoconjugation
dc.subject Lysine
dc.subject N-Glycoalbumin
dc.subject RIKEN click reaction
dc.title Highly reactive “RIKEN click” probe for glycoconjugation on lysines
dc.type Article
dc.relation.ispartofseries-issue 20
dc.relation.ispartofseries-volume 58
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 1929
dc.source.id SCOPUS00404039-2017-58-20-SID85017559448


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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