dc.contributor.author |
Shadrina A. |
|
dc.contributor.author |
Sevost'ianova K. |
|
dc.contributor.author |
Shevela A. |
|
dc.contributor.author |
Soldatsky E. |
|
dc.contributor.author |
Seliverstov E. |
|
dc.contributor.author |
Demekhova M. |
|
dc.contributor.author |
Shonov O. |
|
dc.contributor.author |
Ilyukhin E. |
|
dc.contributor.author |
Smetanina M. |
|
dc.contributor.author |
Voronina E. |
|
dc.contributor.author |
Pikalov I. |
|
dc.contributor.author |
Zolotukhin I. |
|
dc.contributor.author |
Filipenko M. |
|
dc.date.accessioned |
2018-09-19T21:14:31Z |
|
dc.date.available |
2018-09-19T21:14:31Z |
|
dc.date.issued |
2016 |
|
dc.identifier.issn |
1354-750X |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/143669 |
|
dc.description.abstract |
© 2016 Informa UK Limited, trading as Taylor & Francis GroupObjectives: The objective of this study was to study the association of polymorphisms MTHFR C677T (rs1801133) and MTR A2756G (rs1805087) with the risk of varicose veins in ethnical Russians. Methods: We genotyped 475 patients with varicose veins, 168 individual without chronic venous disease, and the population-based group of 896 subjects. Association was studied using logistic regression analysis adopting co-dominant, additive, recessive, and dominant models of inheritance. Results: None of the polymorphisms showed a statistically significant association with the risk of varicose veins. Conclusions: Our results provide evidence that the studied polymorphisms do not contribute to genetic susceptibility to varicose veins in ethnical Russians. |
|
dc.relation.ispartofseries |
Biomarkers |
|
dc.subject |
Association |
|
dc.subject |
folate-metabolizing genes |
|
dc.subject |
SNP |
|
dc.title |
Polymorphisms in the MTHFR and MTR genes and the risk of varicose veins in ethnical Russians |
|
dc.type |
Article in Press |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
1 |
|
dc.source.id |
SCOPUS1354750X-2016-SID84964446331 |
|