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Polymorphisms in the MTHFR and MTR genes and the risk of varicose veins in ethnical Russians
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| dc.contributor.author | Shadrina A. | |
| dc.contributor.author | Sevost'ianova K. | |
| dc.contributor.author | Shevela A. | |
| dc.contributor.author | Soldatsky E. | |
| dc.contributor.author | Seliverstov E. | |
| dc.contributor.author | Demekhova M. | |
| dc.contributor.author | Shonov O. | |
| dc.contributor.author | Ilyukhin E. | |
| dc.contributor.author | Smetanina M. | |
| dc.contributor.author | Voronina E. | |
| dc.contributor.author | Pikalov I. | |
| dc.contributor.author | Zolotukhin I. | |
| dc.contributor.author | Filipenko M. | |
| dc.date.accessioned | 2018-09-19T21:14:29Z | |
| dc.date.available | 2018-09-19T21:14:29Z | |
| dc.date.issued | 2016 | |
| dc.identifier.issn | 1354-750X | |
| dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/143668 | |
| dc.description.abstract | © 2016 Informa UK Limited, trading as Taylor & Francis Group.Objectives: The objective of this study was to study the association of polymorphisms MTHFR C677T (rs1801133) and MTR A2756G (rs1805087) with the risk of varicose veins in ethnical Russians. Methods: We genotyped 475 patients with varicose veins, 168 individual without chronic venous disease, and the population-based group of 896 subjects. Association was studied using logistic regression analysis adopting co-dominant, additive, recessive, and dominant models of inheritance. Results: None of the polymorphisms showed a statistically significant association with the risk of varicose veins. Conclusions: Our results provide evidence that the studied polymorphisms do not contribute to genetic susceptibility to varicose veins in ethnical Russians. | |
| dc.relation.ispartofseries | Biomarkers | |
| dc.subject | Association | |
| dc.subject | folate-metabolizing genes | |
| dc.subject | SNP | |
| dc.title | Polymorphisms in the MTHFR and MTR genes and the risk of varicose veins in ethnical Russians | |
| dc.type | Article | |
| dc.relation.ispartofseries-issue | 7 | |
| dc.relation.ispartofseries-volume | 21 | |
| dc.collection | Публикации сотрудников КФУ | |
| dc.relation.startpage | 619 | |
| dc.source.id | SCOPUS1354750X-2016-21-7-SID84964446331 |
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Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.