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Exploring the glycan interaction in vivo: Future prospects of neo-glycoproteins for diagnostics

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dc.contributor.author Ogura A.
dc.contributor.author Kurbangalieva A.
dc.contributor.author Tanaka K.
dc.date.accessioned 2018-09-19T20:42:48Z
dc.date.available 2018-09-19T20:42:48Z
dc.date.issued 2016
dc.identifier.issn 0959-6658
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/143168
dc.description.abstract © 2016 The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Herein the biodistributions and in vivo kinetics of chemically prepared neoglycoproteins are reviewed. Chemical methods can be used to conjugate various mono- and oligosaccharides onto a protein surface. The kinetics and organ-specific accumulation profiles of these glycoconjugates, which are introduced through intravenous injections, have been analyzed using conventional dissection studies as well as noninvasive methods such as single photon emission computed tomography, positron emission tomography and fluorescence imaging. These studies suggest that glycan-dependent protein distribution kinetics may be useful for pharmacological and diagnostic applications.
dc.relation.ispartofseries Glycobiology
dc.subject albumin
dc.subject in vivo imaging
dc.subject N-glycans
dc.subject neoglycoprotein
dc.subject tumor targeting
dc.title Exploring the glycan interaction in vivo: Future prospects of neo-glycoproteins for diagnostics
dc.type Review
dc.relation.ispartofseries-issue 8
dc.relation.ispartofseries-volume 26
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 804
dc.source.id SCOPUS09596658-2016-26-8-SID84988382924


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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