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An investigation of antigenotoxic properties of plant extracts of Chelidonium majus L., Plantago major L. and Tussilago farfara L

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dc.contributor.author Karamova N.
dc.contributor.author Fatykhova D.
dc.contributor.author Abdrakhimova Y.
dc.contributor.author Il'inskaya O.
dc.date.accessioned 2018-09-18T20:48:50Z
dc.date.available 2018-09-18T20:48:50Z
dc.date.issued 2011
dc.identifier.issn 2079-0597
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/142424
dc.description.abstract The antigenotoxic properties of the sap from three medicinal plants, the greater celandine (Chelidonium majus L.), the greater plantain (Plantago major L.), and coltsfoot (Tussilago farfara L.), were studied using two bacterial test systems (SOS chromotest and Rec assay). It was determined using the combined effect of the plant sap and model genotoxicants on the cells of test strains that the plant sap of the greater celandine reveals a dismutagenic effect decreasing the genotoxic effect of nalidixic acid in the SOS chromotest and furacilin in the Rec assay. The plants sap of the greater celandine and coltsfoot (in 1: 10 and 1: 100 dilutions) demonstrated a bioantimutagenic effect in the SOS chromotest because pre-incubation of the E. coli PQ37 cells test strain with the sap of these plants resulted in a significant decrease of the genotoxic effect of nalidixic acid. The antigenotoxic effect of the greater plantain sap was not statistically significant in both test systems. Possible mechanisms of determining the antigenotoxic properties of the plant sap from greater celandine and coltsfoot are discussed. © 2011 Pleiades Publishing, Ltd.
dc.relation.ispartofseries Russian Journal of Genetics: Applied Research
dc.subject antigenotoxic effect
dc.subject Chelidonium majus L.
dc.subject plant sap
dc.subject Plantago major L.
dc.subject Rec assay
dc.subject SOS chromotest
dc.subject Tussilago farfara L.
dc.title An investigation of antigenotoxic properties of plant extracts of Chelidonium majus L., Plantago major L. and Tussilago farfara L
dc.type Article
dc.relation.ispartofseries-issue 5
dc.relation.ispartofseries-volume 1
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 371
dc.source.id SCOPUS20790597-2011-1-5-SID84864767324


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  • Публикации сотрудников КФУ Scopus [17617]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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