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Adaptation of mycoplasmas to antimicrobial agents: Acholeplasma laidlawii extracellular vesicles mediate the export of ciprofloxacin and a mutant gene related to the antibiotic target

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dc.contributor.author Medvedeva E.
dc.contributor.author Baranova N.
dc.contributor.author Mouzykantov A.
dc.contributor.author Grigorieva T.
dc.contributor.author Davydova M.
dc.contributor.author Trushin M.
dc.contributor.author Chernova O.
dc.contributor.author Chernov V.
dc.date.accessioned 2018-09-18T20:36:02Z
dc.date.available 2018-09-18T20:36:02Z
dc.date.issued 2014
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/141563
dc.description.abstract This study demonstrated that extracellular membrane vesicles are involved with the development of resistance to fluoroquinolones by mycoplasmas (class Mollicutes). This study assessed the differences in susceptibility to ciprofloxacin among strains of Acholeplasma laidlawii PG8. The mechanisms of mycoplasma resistance to antibiotics may be associated with a mutation in a gene related to the target of quinolones, which could modulate the vesiculation level. A. laidlawii extracellular vesicles mediated the export of the nucleotide sequences of the antibiotic target gene as well as the traffic of ciprofloxacin. These results may facilitate the development of effective approaches to control mycoplasma infections, as well as the contamination of cell cultures and vaccine preparations. © 2014 Elena S. Medvedeva et al.
dc.title Adaptation of mycoplasmas to antimicrobial agents: Acholeplasma laidlawii extracellular vesicles mediate the export of ciprofloxacin and a mutant gene related to the antibiotic target
dc.type Article
dc.relation.ispartofseries-volume 2014
dc.collection Публикации сотрудников КФУ
dc.source.id SCOPUS-2014-2014-SID84896840290


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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