Электронный архив

High-definition electrocardiography potential in identifying the reasons for unstable clinical course of coronary heart disease

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dc.contributor.author Latfullin I.
dc.contributor.author Kim Z.
dc.contributor.author Teptin G.
dc.contributor.author Mamedova L.
dc.contributor.author Khromova A.
dc.date.accessioned 2018-09-18T20:24:24Z
dc.date.available 2018-09-18T20:24:24Z
dc.date.issued 2011
dc.identifier.issn 1728-8800
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/139552
dc.description.abstract Aim: To investigate the correlation between clinical and morphological characteristics of coronary heart disease (CHD) and high-definition electrocardiography (HD-ECG) parameters. Material and methods: In total, 85 patients with unstable angina and ST segment depression (ST-UA) underwent HD-ECG during the angina attack, with late ventricular potential (LVP) analysis. One-year survival data were also analysed. Post-mortem histological examination of cardiac tissue was performed in 6 patients with ST-UA. Results: The important morphologic features of ST-UA included cardiomyocyte (CMC) dystrophy, due to acute and chronic myocardial ischemia, and acute injury in the cardiac conduction areas. LVPs were registered in 27 % of the ST-UA patients, mostly among people with transient myocardial ischemia (69,57 %). In patients who previously underwent myocardial infarction, LVP prevalence was lower (28,57 %). At the early stages of hospitalization, LVP were registered in 14 patients (60,87 %), while pharmacotherapy and clinical course stabilization were associated with decreased LVP prevalence (21,74 %). The study results suggest that in patients with acute coronary syndrome, LVP registration predicts not an adverse outcome, but a better prognosis. Conclusion: ST-UA is characterised by typical changes of CMC and myocardial stroma in posterior septal area, which result in metabolic, energetic, and electrical myocardial instability. LVPs could be used as a marker of functional (ischemic) myocardial heterogeneity in patients with ST-UA. LVP registration could be associated with a better prognosis in this clinical group.
dc.relation.ispartofseries Cardiovascular Therapy and Prevention (Russian Federation)
dc.subject High-definition electrocardiography
dc.subject Late ventricular potentials
dc.subject ST segment depression
dc.subject Unstable angina
dc.title High-definition electrocardiography potential in identifying the reasons for unstable clinical course of coronary heart disease
dc.type Article
dc.relation.ispartofseries-issue 3
dc.relation.ispartofseries-volume 10
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 51
dc.source.id SCOPUS17288800-2011-10-3-SID84907939488


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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