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Lipoplexes of dicationic gemini surfactants with DNA: Structural features of DNA compaction and transfection efficiency

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dc.contributor.author Faizullin D.
dc.contributor.author Zuev Y.
dc.contributor.author Zakharova L.
dc.contributor.author Pokrovsky A.
dc.contributor.author Korobeinikov V.
dc.contributor.author Mukhametzyanov T.
dc.contributor.author Konovalov A.
dc.date.accessioned 2018-09-18T20:24:01Z
dc.date.available 2018-09-18T20:24:01Z
dc.date.issued 2015
dc.identifier.issn 1607-6729
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/139485
dc.description.abstract © 2015, Pleiades Publishing, Ltd. The internal structure of DNA lipoplexes with hydroxyethylated alkylammonium gemini surfactants (GS) with high transfection activity was studied by circular dichroism. It was shown that the efficiency of transfection of HEK293T cells with the pEGFP-N1 circular plasmid was different from zero only in the region of existence of chiral supramolecular DNA-GS complexes and reaches a maximum at concentrations at which the spontaneous aggregation of components is observed.
dc.relation.ispartofseries Doklady Biochemistry and Biophysics
dc.title Lipoplexes of dicationic gemini surfactants with DNA: Structural features of DNA compaction and transfection efficiency
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 465
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 432
dc.source.id SCOPUS16076729-2015-465-1-SID84952935885


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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