Lipoplexes of dicationic gemini surfactants with DNA: Structural features of DNA compaction and transfection efficiency

dc.contributor.author	Faizullin D.
dc.contributor.author	Zuev Y.
dc.contributor.author	Zakharova L.
dc.contributor.author	Pokrovsky A.
dc.contributor.author	Korobeinikov V.
dc.contributor.author	Mukhametzyanov T.
dc.contributor.author	Konovalov A.
dc.date.accessioned	2018-09-18T20:24:01Z
dc.date.available	2018-09-18T20:24:01Z
dc.date.issued	2015
dc.identifier.issn	1607-6729
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/139485
dc.description.abstract	© 2015, Pleiades Publishing, Ltd. The internal structure of DNA lipoplexes with hydroxyethylated alkylammonium gemini surfactants (GS) with high transfection activity was studied by circular dichroism. It was shown that the efficiency of transfection of HEK293T cells with the pEGFP-N1 circular plasmid was different from zero only in the region of existence of chiral supramolecular DNA-GS complexes and reaches a maximum at concentrations at which the spontaneous aggregation of components is observed.
dc.relation.ispartofseries	Doklady Biochemistry and Biophysics
dc.title	Lipoplexes of dicationic gemini surfactants with DNA: Structural features of DNA compaction and transfection efficiency
dc.type	Article
dc.relation.ispartofseries-issue	1
dc.relation.ispartofseries-volume	465
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	432
dc.source.id	SCOPUS16076729-2015-465-1-SID84952935885

Файлы в этом документе

Размер: 43.80Kb

Формат: PDF

Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.