Plasmacytoid dendritic cells of the gut: Relevance to immunity and pathology

dc.contributor.author	Lombardi V.
dc.contributor.author	Khaiboullina S.
dc.date.accessioned	2018-09-18T20:23:04Z
dc.date.available	2018-09-18T20:23:04Z
dc.date.issued	2014
dc.identifier.issn	1521-6616
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/139322
dc.description.abstract	Plasmacytoid dendritic cells (pDCs) are bone marrow-derived immune cells with the ability to express copious amounts of type I and III interferon (IFN) and can differentiate into antigen-presenting dendritic cells as a result of stimulation by pathogen-derived nucleic acid. These powerful combined functionalities allow pDCs to bridge the innate and adaptive immune systems resulting in a concerted pathogen response. The contribution of pDCs to gastrointestinal immunity is only now being elucidated and is proving to be a critical component in systemic immunity. This review will explore the immunology of pDCs and will discuss their involvement in human disease and tolerance with an emphasis on those in the gastrointestinal lymphoid tissue. © 2014 .
dc.relation.ispartofseries	Clinical Immunology
dc.subject	Autoimmunity
dc.subject	GALT;
dc.subject	Gut;
dc.subject	Interferon;
dc.subject	PDC;
dc.subject	Tolerance;
dc.title	Plasmacytoid dendritic cells of the gut: Relevance to immunity and pathology
dc.type	Review
dc.relation.ispartofseries-issue	1
dc.relation.ispartofseries-volume	153
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	165
dc.source.id	SCOPUS15216616-2014-153-1-SID84900019211

Файлы в этом документе

Имя: SCOPUS15216616-20 ...

Размер: 132.5Kb

Формат: PDF

Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.