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dc.contributor.author Blatt N.
dc.contributor.author Mingaleeva R.
dc.contributor.author Khaiboullina S.
dc.contributor.author Kotlyar A.
dc.contributor.author Lombardi V.
dc.contributor.author Rizvanov A.
dc.date.accessioned 2018-09-18T20:19:43Z
dc.date.available 2018-09-18T20:19:43Z
dc.date.issued 2013
dc.identifier.issn 1097-8135
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/138762
dc.description.abstract Animal models have been indispensable when conducting research to further the understanding of cancer biology and when developing anticancer drugs. This article presents an overview of the most commonly utilized animal models for preclinical screening of anticancer agents. These models can be roughly divided into two groups: models in which tumors are transplanted into mice, and models in which tumors develop in situ, either spontaneously or induced. Special attention is paid to the widely used subcutaneous xenotransplant and the orthotopic tumor models. We will also highlight the development and use of genetically modified mice.
dc.relation.ispartofseries Life Science Journal
dc.subject Animal models
dc.subject Anticancer drugs
dc.subject Cancer
dc.subject Oncology
dc.subject Test-systems
dc.subject Toxicity
dc.subject Tumor
dc.title In vivo screening models of anticancer drugs
dc.type Article
dc.relation.ispartofseries-issue 4
dc.relation.ispartofseries-volume 10
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 1892
dc.source.id SCOPUS10978135-2013-10-4-SID84888116297


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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