dc.contributor.author |
Abdullin T. |
|
dc.contributor.author |
Nikitina I. |
|
dc.contributor.author |
Bondar' O. |
|
dc.date.accessioned |
2018-09-18T20:14:34Z |
|
dc.date.available |
2018-09-18T20:14:34Z |
|
dc.date.issued |
2008 |
|
dc.identifier.issn |
1061-9348 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/137873 |
|
dc.description.abstract |
The possibility of detecting DNA depurination products on a glassy carbon electrode modified with carbon nanotubes (CNTs) was revealed. Adenine and a guanine DNA nucleotide were oxidized at similar potentials of about +1.1 V against Ag/AgCl; this fact did not allow us to detect adenine in the presence of DNA. DNA components did not interfere with the detection of guanine, which was oxidized at +0.9 V. Guanine was strongly adsorbed on the CNT-modified glassy carbon electrode; the oxidation current of guanine was a linear function of the concentration described by the equation i (10-6 A) = 3.21 + 0.44 c (10-6 M), r = 0.963. The results were suitable for the determination of guanine liberated from DNA on the CNT-modified glassy carbon electrode. The procedure developed was applied to evaluate the rates of DNA depurination under various conditions. © 2008 MAIK Nauka. |
|
dc.relation.ispartofseries |
Journal of Analytical Chemistry |
|
dc.title |
Detection of DNA depurination with the use of an electrode modified with carbon nanotubes |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
7 |
|
dc.relation.ispartofseries-volume |
63 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
690 |
|
dc.source.id |
SCOPUS10619348-2008-63-7-SID46449123175 |
|