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Genotoxicological safety assessment of a new antiparkinsonian substance ((1r,2r,6s)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol)
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| dc.contributor.author | Trushin M. | |
| dc.contributor.author | Ardashov O. | |
| dc.contributor.author | Volcho K. | |
| dc.contributor.author | Arkharova I. | |
| dc.contributor.author | Salakhutdinov N. | |
| dc.date.accessioned | 2018-09-18T20:13:29Z | |
| dc.date.available | 2018-09-18T20:13:29Z | |
| dc.date.issued | 2013 | |
| dc.identifier.issn | 1817-3055 | |
| dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/137722 | |
| dc.description.abstract | Parkinson's disease (PD) is a neurodegenerative condition of unknown etiology. This article is devoted to special genotoxicological testing of a new substance with antiparkinsonian activity. It was assessed using Allium cepa-test system. As a result of study of the effect (1R, 2R, 6S)-3-methyl-6-(prop-1-en-2-yl) cyclohex-3-ene-1,2-diol in cell model object (Allium cepa) we revealed two distinctive features of the effects of substance-itotoxic effect and no increase in the frequency of genetic disorders with increasing concentration of the substance. In general, the tested substance seems safe. © IDOSI Publications, 2013. | |
| dc.relation.ispartofseries | World Journal of Medical Sciences | |
| dc.subject | Diol | |
| dc.subject | Genotoxicological safety | |
| dc.subject | Mutations | |
| dc.subject | Parkinson's disease | |
| dc.subject | Treatment | |
| dc.title | Genotoxicological safety assessment of a new antiparkinsonian substance ((1r,2r,6s)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol) | |
| dc.type | Article | |
| dc.relation.ispartofseries-issue | 4 | |
| dc.relation.ispartofseries-volume | 8 | |
| dc.collection | Публикации сотрудников КФУ | |
| dc.relation.startpage | 355 | |
| dc.source.id | SCOPUS18173055-2013-8-4-SID84880648635 |
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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.