dc.contributor.author |
Trushin M. |
|
dc.contributor.author |
Ardashov O. |
|
dc.contributor.author |
Volcho K. |
|
dc.contributor.author |
Arkharova I. |
|
dc.contributor.author |
Salakhutdinov N. |
|
dc.date.accessioned |
2018-09-18T20:13:29Z |
|
dc.date.available |
2018-09-18T20:13:29Z |
|
dc.date.issued |
2013 |
|
dc.identifier.issn |
1817-3055 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/137722 |
|
dc.description.abstract |
Parkinson's disease (PD) is a neurodegenerative condition of unknown etiology. This article is devoted to special genotoxicological testing of a new substance with antiparkinsonian activity. It was assessed using Allium cepa-test system. As a result of study of the effect (1R, 2R, 6S)-3-methyl-6-(prop-1-en-2-yl) cyclohex-3-ene-1,2-diol in cell model object (Allium cepa) we revealed two distinctive features of the effects of substance-itotoxic effect and no increase in the frequency of genetic disorders with increasing concentration of the substance. In general, the tested substance seems safe. © IDOSI Publications, 2013. |
|
dc.relation.ispartofseries |
World Journal of Medical Sciences |
|
dc.subject |
Diol |
|
dc.subject |
Genotoxicological safety |
|
dc.subject |
Mutations |
|
dc.subject |
Parkinson's disease |
|
dc.subject |
Treatment |
|
dc.title |
Genotoxicological safety assessment of a new antiparkinsonian substance ((1r,2r,6s)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol) |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
4 |
|
dc.relation.ispartofseries-volume |
8 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
355 |
|
dc.source.id |
SCOPUS18173055-2013-8-4-SID84880648635 |
|