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In vivo kinetics and biodistribution analysis of neoglycoproteins: Effects of chemically introduced glycans on proteins

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dc.contributor.author Ogura A.
dc.contributor.author Kurbangalieva A.
dc.contributor.author Tanaka K.
dc.date.accessioned 2018-09-18T20:08:12Z
dc.date.available 2018-09-18T20:08:12Z
dc.date.issued 2014
dc.identifier.issn 0282-0080
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/136862
dc.description.abstract Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies clearly show the glycan-structure dependency on protein kinetics, which will provide promising possibilities for pharmacological and diagnostic applications. © 2014 Springer Science+Business Media.
dc.relation.ispartofseries Glycoconjugate Journal
dc.subject Albumin
dc.subject Bioconjugation
dc.subject Biodistribution
dc.subject Chemical reaction
dc.subject In vivo imaging
dc.subject N-Glycans
dc.subject Neoglycoprotein
dc.subject Tumor targeting
dc.title In vivo kinetics and biodistribution analysis of neoglycoproteins: Effects of chemically introduced glycans on proteins
dc.type Article
dc.relation.ispartofseries-issue 4
dc.relation.ispartofseries-volume 31
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 273
dc.source.id SCOPUS02820080-2014-31-4-SID84901926759


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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