Binase and other microbial RNases as potential anticancer agents

dc.contributor.author	Makarov A.
dc.contributor.author	Kolchinsky A.
dc.contributor.author	Ilinskaya O.
dc.date.accessioned	2018-09-18T20:07:30Z
dc.date.available	2018-09-18T20:07:30Z
dc.date.issued	2008
dc.identifier.issn	0265-9247
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/136745
dc.description.abstract	Some RNases possess preferential cytotoxicity against malignant cells. The best known of these RNases, onconase, was isolated from frog oocytes; and is in clinical trials as anticancer therapy. Here we propose an alternative platform for anticancer therapy based on T1 RNases of microbial origin, in particular binase from Bacillus Intermedius and RNase Sa from Streptomyces aureofaciens. We discuss their advantages and the most promising directions of research for their potential clinical applications. © 2008 Wiley Periodicals, Inc.
dc.relation.ispartofseries	BioEssays
dc.title	Binase and other microbial RNases as potential anticancer agents
dc.type	Article
dc.relation.ispartofseries-issue	8
dc.relation.ispartofseries-volume	30
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	781
dc.source.id	SCOPUS02659247-2008-30-8-SID48949094215

Файлы в этом документе

Имя: SCOPUS02659247-20 ...

Размер: 43.64Kb

Формат: PDF

Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.