Effect of α2-adrenoceptor stimulation on cardiac activity in rats

dc.contributor.author	Zefirov T.
dc.contributor.author	Ziyatdinova N.
dc.contributor.author	Khisamieva L.
dc.contributor.author	Zefirov A.
dc.date.accessioned	2018-09-18T20:02:27Z
dc.date.available	2018-09-18T20:02:27Z
dc.date.issued	2014
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135985
dc.description.abstract	We studied the effect of α2-adrenoceptor stimulation with clonidine on BP and cardiac activity in rats. Variations in BP and chronotropism of the heart were studied in vivo after bolus injection of clonidine. In vitro experiments were performed to evaluate a dose-dependent change in myocardial contractility of the atria and ventricles after treatment with clonidine in concentrations of 10-9-10-5 M. α2- Adrenoceptor stimulation with clonidine had a negative chronotropic and inotropic effect and induced the decrease in systolic BP of rats. © 2014 Springer Science+Business Media.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	Blood pressure
dc.subject	Chronotropism
dc.subject	Heart
dc.subject	Inotropy
dc.subject	Rat
dc.title	Effect of α2-adrenoceptor stimulation on cardiac activity in rats
dc.type	Article
dc.relation.ispartofseries-issue	2
dc.relation.ispartofseries-volume	157
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	194
dc.source.id	SCOPUS00074888-2014-157-2-SID84904293001

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.