Age-related peculiarities of inotropic response of rat myocardium to selective block of M1-cholinoreceptors

dc.contributor.author	Zefirov T.
dc.contributor.author	Ziyatdinova N.
dc.contributor.author	Zefirov A.
dc.date.accessioned	2018-09-18T20:02:25Z
dc.date.available	2018-09-18T20:02:25Z
dc.date.issued	2013
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135980
dc.description.abstract	In vitro effect of M1-cholinoreceptor blockade on the cardiac inotropic function was examined in rats aging 1, 3, 6, 8, and 20 weeks. In 1- and 3-week old rat pups, the sympathetic control of the heart has not developed, the age of 7-8 weeks being pubertal. Adult 20-week rats were used as the controls. In rats of all age groups, preliminary blockade of M1-cholinoreceptors did not prevent the inhibitory effect of carbacholine on contractility of the atrial and ventricular myocardium. The inhibitory effect of pirenzepine on the contractile force of ventricular myocardium was revealed in 6-week rats. © 2013 Springer Science+Business Media New York.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	heart
dc.subject	inotropy
dc.subject	muscarinic cholinoreceptors
dc.subject	postnatal ontogeny
dc.subject	rat
dc.title	Age-related peculiarities of inotropic response of rat myocardium to selective block of M1-cholinoreceptors
dc.type	Article
dc.relation.ispartofseries-issue	6
dc.relation.ispartofseries-volume	155
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	708
dc.source.id	SCOPUS00074888-2013-155-6-SID84888306021

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.