Blockade of different subtypes of α1-adrenoceptors produces opposite effect on heart chronotropy in newborn rats

dc.contributor.author	Ziyatdinova N.
dc.contributor.author	Dementieva R.
dc.contributor.author	Fashutdinov L.
dc.contributor.author	Zefirov T.
dc.date.accessioned	2018-09-18T20:02:22Z
dc.date.available	2018-09-18T20:02:22Z
dc.date.issued	2012
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135971
dc.description.abstract	We compared the effects of blockade of α1A-, α1-, and α1D-subtypes of α1- adrenoceptors on the cardiac rhythm in newborn rats. Different responses of the heart were observed after blockade of several subtypes of α1- adrenoceptors. Administration of WB 4101, a selective blocker of α1A-adrenoceptors, increased heart rate, while blockade of α1AD-adrenoceptors with BMY 7378 decelerated of heart rhythm. Blockade of α1-adrenoceptors with chloroethylclonidine produced no significant effects on heart chronotropy. © 2012 Springer Science+Business Media New York.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	α1-adrenoceptor
dc.subject	heart
dc.subject	ontogeny
dc.subject	rat
dc.subject	sympathetic regulation
dc.title	Blockade of different subtypes of α1-adrenoceptors produces opposite effect on heart chronotropy in newborn rats
dc.type	Article
dc.relation.ispartofseries-issue	2
dc.relation.ispartofseries-volume	154
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	184
dc.source.id	SCOPUS00074888-2012-154-2-SID84878404552

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.