ATP as modulator of carbacholine effect on contractility of rat myocardium in postnatal ontogeny

dc.contributor.author	Anikina T.
dc.contributor.author	Sitdikov F.
dc.contributor.author	Zverev A.
dc.date.accessioned	2018-09-18T20:02:19Z
dc.date.available	2018-09-18T20:02:19Z
dc.date.issued	2009
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135963
dc.description.abstract	We studied combined effect of 2-m-ATP, P 2 receptor agonist, and carbacholine, muscarinic M 2 cholinoreceptor agonist, on contractility of rat myocardium during the postnatal ontogeny. Activation of P 2 receptors can stimulate or attenuate the effects of carbacholine depending on animal age. 2-m-ATP potentiates the inhibitory effect of carbacholine on myocardial contractility in 14- and 100-day-old rats. In 21-day-old rats, activation of P 2 receptors prevented the negative effect of carbacholine on myocardial contractility. Activation of muscarinic M 2 receptors inhibited the inotropic effect of purine in all age groups. © 2009 Springer Science+Business Media, Inc.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	Contractility
dc.subject	Muscarinic cholinoceptors
dc.subject	Myocardium
dc.subject	Ontogeny
dc.subject	P 2 receptors
dc.title	ATP as modulator of carbacholine effect on contractility of rat myocardium in postnatal ontogeny
dc.type	Article
dc.relation.ispartofseries-issue	2
dc.relation.ispartofseries-volume	148
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	210
dc.source.id	SCOPUS00074888-2009-148-2-SID74949134174

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.