Role of P2X receptors in positive inotropic effect of rat myocardium during ontogeny

dc.contributor.author	Zverev A.
dc.contributor.author	Anikina T.
dc.contributor.author	Sitdicov F.
dc.date.accessioned	2018-09-18T20:02:19Z
dc.date.available	2018-09-18T20:02:19Z
dc.date.issued	2008
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135962
dc.description.abstract	Experiments with selective agonists and antagonists of purinoceptors allowed us to evaluate the subtype of P2X receptors. We showed that the myocardium of 14-100-day-old rats contains functionally active P2X 1 receptors. These receptors are involved in the realization of the positive inotropic effect of the atria and ventricles. Selective P2X 1 receptor agonist β,γ-methylene-ATP induced a dose-dependent increase in the strength of atrial and ventricular contractions. P2X 1 receptor antagonist TNP-ATP abolished the effect of the agonist in rats of all age groups. © Springer Science+Business Media, Inc. 2008.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	Myocardial contractility
dc.subject	Ontogeny
dc.subject	P2X receptors
dc.title	Role of P2X receptors in positive inotropic effect of rat myocardium during ontogeny
dc.type	Article
dc.relation.ispartofseries-issue	2
dc.relation.ispartofseries-volume	145
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	174
dc.source.id	SCOPUS00074888-2008-145-2-SID50649104575

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.