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Effect of ATP and its analogs on contractility of rat myocardium during ontogeny

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dc.contributor.author Anikina T.
dc.contributor.author Bilalova G.
dc.contributor.author Zverev A.
dc.contributor.author Sitdikov F.
dc.date.accessioned 2018-09-18T20:02:17Z
dc.date.available 2018-09-18T20:02:17Z
dc.date.issued 2007
dc.identifier.issn 0007-4888
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/135958
dc.description.abstract The effects of P2-receptor agonists on myocardial contractility were examined in rats aging 14-100 days. ATP and its stable analog 2-methylthio-ATP potentiated the contraction force of isolated myocardial strips in a dose-dependent manner. The agonist concentrations producing the positive inotropic effect increased from days 14 to 100 of life. The efficiency of extracellular purines depends on animal age: in 14-and 56-day rats the positive inotropic effects of ATP and 2-methylthio-ATP were similar, while in 100-day rats ATP produced more pronounced effect than 2-methylthio-ATP. © Springer Science+Business Media, Inc. 2007.
dc.relation.ispartofseries Bulletin of Experimental Biology and Medicine
dc.subject ATP
dc.subject Contractility
dc.subject Myocardium
dc.subject Ontogeny
dc.subject P2-receptors
dc.title Effect of ATP and its analogs on contractility of rat myocardium during ontogeny
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 144
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 4
dc.source.id SCOPUS00074888-2007-144-1-SID36349031745


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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