dc.contributor.author |
Anikina T. |
|
dc.contributor.author |
Bilalova G. |
|
dc.contributor.author |
Zverev A. |
|
dc.contributor.author |
Sitdikov F. |
|
dc.date.accessioned |
2018-09-18T20:02:17Z |
|
dc.date.available |
2018-09-18T20:02:17Z |
|
dc.date.issued |
2007 |
|
dc.identifier.issn |
0007-4888 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/135958 |
|
dc.description.abstract |
The effects of P2-receptor agonists on myocardial contractility were examined in rats aging 14-100 days. ATP and its stable analog 2-methylthio-ATP potentiated the contraction force of isolated myocardial strips in a dose-dependent manner. The agonist concentrations producing the positive inotropic effect increased from days 14 to 100 of life. The efficiency of extracellular purines depends on animal age: in 14-and 56-day rats the positive inotropic effects of ATP and 2-methylthio-ATP were similar, while in 100-day rats ATP produced more pronounced effect than 2-methylthio-ATP. © Springer Science+Business Media, Inc. 2007. |
|
dc.relation.ispartofseries |
Bulletin of Experimental Biology and Medicine |
|
dc.subject |
ATP |
|
dc.subject |
Contractility |
|
dc.subject |
Myocardium |
|
dc.subject |
Ontogeny |
|
dc.subject |
P2-receptors |
|
dc.title |
Effect of ATP and its analogs on contractility of rat myocardium during ontogeny |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
1 |
|
dc.relation.ispartofseries-volume |
144 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
4 |
|
dc.source.id |
SCOPUS00074888-2007-144-1-SID36349031745 |
|