Effect of ATP and its analogs on contractility of rat myocardium during ontogeny

dc.contributor.author	Anikina T.
dc.contributor.author	Bilalova G.
dc.contributor.author	Zverev A.
dc.contributor.author	Sitdikov F.
dc.date.accessioned	2018-09-18T20:02:17Z
dc.date.available	2018-09-18T20:02:17Z
dc.date.issued	2007
dc.identifier.issn	0007-4888
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/135958
dc.description.abstract	The effects of P2-receptor agonists on myocardial contractility were examined in rats aging 14-100 days. ATP and its stable analog 2-methylthio-ATP potentiated the contraction force of isolated myocardial strips in a dose-dependent manner. The agonist concentrations producing the positive inotropic effect increased from days 14 to 100 of life. The efficiency of extracellular purines depends on animal age: in 14-and 56-day rats the positive inotropic effects of ATP and 2-methylthio-ATP were similar, while in 100-day rats ATP produced more pronounced effect than 2-methylthio-ATP. © Springer Science+Business Media, Inc. 2007.
dc.relation.ispartofseries	Bulletin of Experimental Biology and Medicine
dc.subject	ATP
dc.subject	Contractility
dc.subject	Myocardium
dc.subject	Ontogeny
dc.subject	P2-receptors
dc.title	Effect of ATP and its analogs on contractility of rat myocardium during ontogeny
dc.type	Article
dc.relation.ispartofseries-issue	1
dc.relation.ispartofseries-volume	144
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	4
dc.source.id	SCOPUS00074888-2007-144-1-SID36349031745

Файлы в этом документе

Имя: SCOPUS00074888-20 ...

Размер: 43.85Kb

Формат: PDF

Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.