dc.contributor.author |
Khalilov I. |
|
dc.contributor.author |
Sitdikova G. |
|
dc.contributor.author |
Zefirov A. |
|
dc.date.accessioned |
2018-09-17T21:36:34Z |
|
dc.date.available |
2018-09-17T21:36:34Z |
|
dc.date.issued |
1995 |
|
dc.identifier.issn |
0090-2977 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/135206 |
|
dc.description.abstract |
Effects of pyrocatechol on neuromuscular transmission were studied both in the frog pectoral-cutaneous muscle and in the mouse phrenic-diaphragmatic preparation by means of extracellular microelectrode recording of synaptic signals. Pyrocatechol applied in a concentration of 0.05 mM increased the frequency of miniature end-plate currents (MEPC) and the amplitude of end-plate current (EPC) by increasing its quantum content. Pyrocatechol also increased the duration of presynaptic response. When voltage-dependent potassium channels had been blocked, pyrocatechol affected neither the EPC quantum content nor the duration of presynaptic response. It is suggested that the pyrocatechol-induced enhancement of transmitter release results from modulatory effects of pyrocatechol on voltage-dependent potassium current in the membrane of a nerve terminal. © 1995 Plenum Publishing Corporation. |
|
dc.relation.ispartofseries |
Neurophysiology |
|
dc.title |
Effects of pyrocatechol on neuromuscular transmission |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
6 |
|
dc.relation.ispartofseries-volume |
25 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
333 |
|
dc.source.id |
SCOPUS00902977-1995-25-6-SID34249764596 |
|