A New Amperometric Biosensor Based on Platinum(II) Complex with DNA for Detecting Autoantibodies to DNA

dc.contributor.author	Babkina S.
dc.contributor.author	Ulakhovich N.
dc.contributor.author	Medyantseva E.
dc.contributor.author	Klimovich O.
dc.date.accessioned	2018-09-17T20:45:24Z
dc.date.available	2018-09-17T20:45:24Z
dc.date.issued	1998
dc.identifier.issn	0555-1099
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/133999
dc.description.abstract	A biochemical biosensor was developed on the basis of a steady-state Hg-film electrode and either DNA molecules or antibodies to DNA immobilized in a cellulose nitrate film. This biosensor is designed to measure the concentration of DNA (or antibodies to DNA), and it can be used in the diagnosis of autoimmune diseases. Electric current of catalytic H2 evolution caused by complexing between DNA (antibodies to DNA) and Pt(II) was used as an analytical signal. The detection sensitivity threshold for DNA and antibodies to DNA was 10 and 0.075 μg/ml, respectively.
dc.relation.ispartofseries	Prikladnaya Biokhimiya i Mikrobiologiya
dc.title	A New Amperometric Biosensor Based on Platinum(II) Complex with DNA for Detecting Autoantibodies to DNA
dc.type	Article
dc.relation.ispartofseries-issue	5
dc.relation.ispartofseries-volume	34
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	575
dc.source.id	SCOPUS05551099-1998-34-5-SID0347649492

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Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.