Kazan Federal University Digital Repository

Hexylresorcinol induces chromosome aberrations in mouse peripheral blood cells

Show simple item record

dc.contributor.author Margulis A.
dc.contributor.author Ozhiganova I.
dc.contributor.author Bushmanova O.
dc.contributor.author Kolpakov A.
dc.contributor.author Il'inskaya O.
dc.date.accessioned 2018-09-17T20:13:52Z
dc.date.available 2018-09-17T20:13:52Z
dc.date.issued 2005
dc.identifier.issn 0016-6758
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/133212
dc.description.abstract Hexylresorcinol has been demonstrated to induce chromosome aberrations in eukaryotic cells at doses of 0.5, 0.05, and 0.005 mg/g body weight. The metabolic transformation of hexylresorcinol in mice decreases its genotoxic effect. The mutagenic effect is retained for three days only after the administration of the highest dose of hexylresorcinol (0.5 mg/g); during the first two days, lower doses are also genotoxic. Therefore, hexylresorcinol doses lower than 0.5 mg/g body weight are metabolized within two days to the extent precluding the expression of the cytotoxic effect. After a single administration to mice, exogenous hexylresorcinol is transformed at a rate of 0.0025-0.025 mg/day.
dc.relation.ispartofseries Genetika
dc.title Hexylresorcinol induces chromosome aberrations in mouse peripheral blood cells
dc.type Article
dc.relation.ispartofseries-issue 8
dc.relation.ispartofseries-volume 41
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 1045
dc.source.id SCOPUS00166758-2005-41-8-SID27744509651


Files in this item

This item appears in the following Collection(s)

  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

Show simple item record

Search DSpace


Advanced Search

Browse

My Account

Statistics