Kazan Federal University Digital Repository

SOS-inducible DNA polymerases and adaptive mutagenesis

Show simple item record

dc.contributor.author Babynin E.
dc.date.accessioned 2018-09-17T20:13:49Z
dc.date.available 2018-09-17T20:13:49Z
dc.date.issued 2004
dc.identifier.issn 0016-6758
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/133211
dc.description.abstract Stability of genomes of living organisms is maintained by various mechanisms that ensure high fidelity of DNA replication. However, cells can reversibly enhance the level of replication errors in response to external factors. As mutable states are potentially involved in carcinogenesis, aging, and resistance for pathogenic agents, the existence of these states is of great importance for human health. A well-known system of inducible mutation is SOS response, whose key component is replication of damaged DNA regions. Inducible mutation implies a contribution of SOS response to the adaptation of a bacterial population to adverse environments. There is ample evidence indicating the primary role of SOS response genes in the phenomenon of adaptive mutation. The involvement of the SOS system in adaptive mutagenesis is discussed.
dc.relation.ispartofseries Genetika
dc.title SOS-inducible DNA polymerases and adaptive mutagenesis
dc.type Review
dc.relation.ispartofseries-issue 5
dc.relation.ispartofseries-volume 40
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 581
dc.source.id SCOPUS00166758-2004-40-5-SID16644376547


Files in this item

This item appears in the following Collection(s)

  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

Show simple item record

Search DSpace


Advanced Search

Browse

My Account

Statistics