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Acetylcholinesterase sensors based on gold electrodes modified with dendrimer and polyaniline: A comparative research

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dc.contributor.author Snejdarkova M.
dc.contributor.author Svobodova L.
dc.contributor.author Evtugyn G.
dc.contributor.author Budnikov H.
dc.contributor.author Karyakin A.
dc.contributor.author Nikolelis D.
dc.contributor.author Hianik T.
dc.date.accessioned 2018-09-17T20:05:17Z
dc.date.available 2018-09-17T20:05:17Z
dc.date.issued 2004
dc.identifier.issn 0003-2670
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/133012
dc.description.abstract Potentiometric and amperometric enzyme sensors based on modified gold electrodes have been developed and compared in pesticide determination. PAMAM dendrimer (generation G4) stabilized with 1-hexadecanethiol was used for the immobilization of acetylcholinesterase from electric eel and choline oxidase from Alcaligenes species in the assembly of amperometric sensor. Polyaniline-doped with camphorsulfonic acid was used to obtain potentiometric response. Trichlorfon, carbofuran and eserine suppress the biosensor response due to their inhibitory effect. The detection limits of 0.003 and 200 nmol l-1 (trichlorfon), 0.04 and 6 nmol l-1 (carbofuran) and 0.1 and 700 nmol l-1 were obtained for amperometric and potentiometric sensors, respectively. The difference in the biosensor behavior and the high sensitivity of the dendrimer modified sensor to the inhibitors is due to the specific organization of protein layer at charged surface of the modifier macromolecules. © 2004 Elsevier B.V. All rights reserved.
dc.relation.ispartofseries Analytica Chimica Acta
dc.subject Cholinesterase
dc.subject Dendrimers
dc.subject Enzyme sensor
dc.subject Polyaniline
dc.title Acetylcholinesterase sensors based on gold electrodes modified with dendrimer and polyaniline: A comparative research
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 514
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 79
dc.source.id SCOPUS00032670-2004-514-1-SID2442478089


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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