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Regulatory Profile Changes of Lymphocytes and Peripheral Blood Monocytes in Children with Candidiasis Associated with Chronic Somatic Diseases

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dc.contributor.author Agafonova E.
dc.contributor.author Rizvanova F.
dc.contributor.author Kadyrova A.
dc.contributor.author Abrahamyan L.
dc.date.accessioned 2018-04-05T07:10:36Z
dc.date.available 2018-04-05T07:10:36Z
dc.date.issued 2017
dc.identifier.issn 2191-1630
dc.identifier.uri http://dspace.kpfu.ru/xmlui/handle/net/130544
dc.description.abstract © 2017, Springer Science+Business Media, LLC. In this paper, we report results of the study of immune parameters with the assessment of regulatory and effector subpopulations of lymphocytes and monocytes with candidiasis in children with chronic somatic diseases (secondary pyelonephritis and obstructive diseases of the upper gastrointestinal tract). Candidiasis was diagnosed by the rising level of circulating Candida albicans mannan antigen and culture mycological research. It was found that the persistence of fungi is associated with differentiated regulatory changes in the structure of subpopulations of lymphocytes and monocytes with preferential increase of immunosuppressive cells (CD4+CD25+hi, CD3+CD16/56+, CD3−CD8+, CD3+4 amid reduction of effector subpopulations of lymphocytes and antigen presenting cells associated with Th1 immune response profile.
dc.relation.ispartofseries BioNanoScience
dc.subject Candidiasis
dc.subject Chronic somatic diseases
dc.subject Subpopulation of lymphocytes and monocytes
dc.title Regulatory Profile Changes of Lymphocytes and Peripheral Blood Monocytes in Children with Candidiasis Associated with Chronic Somatic Diseases
dc.type Article
dc.relation.ispartofseries-issue 4
dc.relation.ispartofseries-volume 7
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 627
dc.source.id SCOPUS21911630-2017-7-4-SID85036642188


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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