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An integrated expression atlas of miRNAs and their promoters in human and mouse

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dc.contributor.author De Rie D.
dc.contributor.author Abugessaisa I.
dc.contributor.author Alam T.
dc.contributor.author Arner E.
dc.contributor.author Arner P.
dc.contributor.author Ashoor H.
dc.contributor.author Åström G.
dc.contributor.author Babina M.
dc.contributor.author Bertin N.
dc.contributor.author Burroughs A.
dc.contributor.author Carlisle A.
dc.contributor.author Daub C.
dc.contributor.author Detmar M.
dc.contributor.author Deviatiiarov R.
dc.contributor.author Fort A.
dc.contributor.author Gebhard C.
dc.contributor.author Goldowitz D.
dc.contributor.author Guhl S.
dc.contributor.author Ha T.
dc.contributor.author Harshbarger J.
dc.contributor.author Hasegawa A.
dc.contributor.author Hashimoto K.
dc.contributor.author Herlyn M.
dc.contributor.author Heutink P.
dc.contributor.author Hitchens K.
dc.contributor.author Hon C.
dc.contributor.author Huang E.
dc.contributor.author Ishizu Y.
dc.contributor.author Kai C.
dc.contributor.author Kasukawa T.
dc.contributor.author Klinken P.
dc.contributor.author Lassmann T.
dc.contributor.author Lecellier C.
dc.contributor.author Lee W.
dc.contributor.author Lizio M.
dc.contributor.author Makeev V.
dc.contributor.author Mathelier A.
dc.contributor.author Medvedeva Y.
dc.contributor.author Mejhert N.
dc.contributor.author Mungall C.
dc.contributor.author Noma S.
dc.contributor.author Ohshima M.
dc.contributor.author Okada-Hatakeyama M.
dc.contributor.author Persson H.
dc.contributor.author Rizzu P.
dc.contributor.author Roudnicky F.
dc.contributor.author Sætrom P.
dc.contributor.author Sato H.
dc.contributor.author Severin J.
dc.contributor.author Shin J.
dc.contributor.author Swoboda R.
dc.contributor.author Tarui H.
dc.contributor.author Toyoda H.
dc.contributor.author Vitting-Seerup K.
dc.contributor.author Winteringham L.
dc.contributor.author Yamaguchi Y.
dc.contributor.author Yasuzawa K.
dc.contributor.author Yoneda M.
dc.contributor.author Yumoto N.
dc.contributor.author Zabierowski S.
dc.contributor.author Zhang P.
dc.contributor.author Wells C.
dc.contributor.author Summers K.
dc.contributor.author Kawaji H.
dc.contributor.author Sandelin A.
dc.contributor.author Rehli M.
dc.contributor.author Hayashizaki Y.
dc.date.accessioned 2018-04-05T07:09:41Z
dc.date.available 2018-04-05T07:09:41Z
dc.date.issued 2017
dc.identifier.issn 1087-0156
dc.identifier.uri http://dspace.kpfu.ru/xmlui/handle/net/129902
dc.description.abstract © 2017 Nature America, Inc., part of Springer Nature. MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) project, we created an integrated expression atlas of miRNAs and their promoters by deep-sequencing 492 short RNA (sRNA) libraries, with matching Cap Analysis Gene Expression (CAGE) data, from 396 human and 47 mouse RNA samples. Promoters were identified for 1,357 human and 804 mouse miRNAs and showed strong sequence conservation between species. We also found that primary and mature miRNA expression levels were correlated, allowing us to use the primary miRNA measurements as a proxy for mature miRNA levels in a total of 1,829 human and 1,029 mouse CAGE libraries. We thus provide a broad atlas of miRNA expression and promoters in primary mammalian cells, establishing a foundation for detailed analysis of miRNA expression patterns and transcriptional control regions.
dc.relation.ispartofseries Nature Biotechnology
dc.title An integrated expression atlas of miRNAs and their promoters in human and mouse
dc.type Article
dc.relation.ispartofseries-issue 9
dc.relation.ispartofseries-volume 35
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 872
dc.source.id SCOPUS10870156-2017-35-9-SID85028474852


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  • Публикации сотрудников КФУ Scopus [20180]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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