Photoditazine photodynamic effect on DNA and blood cells of Brachydanio rerio

Abstract

The study is aimed at identifying the morphological and cytogenetic changes in erythrocytes of Brachydanio rerio, arising under the influence of photodynamic effects that models laser modification of blood, with the use of Fotoditazin, a photosensitizer of the chlorine range, and red laser radiation. (Methods of Research) For 15 days, juvenile fish Brachydanio rerio were kept in settled tap water after providing model of laser modification of the blood using Fotoditazin and exposure to laser radiation with the wavelength of 630 nm. The impact on the structure of DNA in the nuclei of red blood cells of Fotoditazin, laser radiation and combined effects of these factors on the changes in the fluorescence spectra of DNA and the color of fluorescence were studied.(Generalization of results and their meaning). It had been shown that separate effects of laser or Fotoditazin did not cause changes in the fluorescence of nuclei of erythrocytes, when the preparations were studied with the use of