Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

Singh Mahavir; Rohde Manfred; Shuralev Eduard Arkadevich; Maringer Marko; Oehlmann Wulf; Steinicke Susanne; Huck Carmen; Wanas Hanaa; Braun Yvonne; Elamin Ayssar A.

dc.contributor	Казанский федеральный университет
dc.contributor.author	Elamin Ayssar A.
dc.contributor.author	Steinicke Susanne
dc.contributor.author	Oehlmann Wulf
dc.contributor.author	Braun Yvonne
dc.contributor.author	Wanas Hanaa
dc.contributor.author	Shuralev Eduard Arkadevich
dc.contributor.author	Huck Carmen
dc.contributor.author	Maringer Marko
dc.contributor.author	Rohde Manfred
dc.contributor.author	Singh Mahavir
dc.date.accessioned	2017-11-21T08:54:45Z
dc.date.available	2017-11-21T08:54:45Z
dc.date.issued	2017
dc.identifier.citation	Elamin A.A. Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa / A.A. Elamin, S. Steinicke, W. Oehlmann, Y. Braun, H. Wanas, E.A. Shuralev, C. Huck, M. Maringer, M. Rohde, M. Singh // PLoS ONE. - 2017. - 12(10): e0186801. DOI: 10.1371/journal.pone.0186801. WOS:000413168100091
dc.identifier.issn	1932-6203
dc.identifier.uri	http://dspace.kpfu.ru/xmlui/handle/net/117107
dc.description.abstract	This study demonstrates that cell wall targets contribute significantly to intracellular survival, in vivo growth, and pathogenesis of P. aeruginosa. In conclusion, these findings establish a link between cell wall targets and virulence of P. aeruginosa and thus may lead to development of novel drugs for the treatment of P. aeruginosa infection.
dc.language.iso	en
dc.relation.ispartofseries	PLos ONE
dc.rights	открытый доступ
dc.subject	ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE
dc.subject	BACTERIAL BIOFILM FORMATION
dc.subject	UDP-N-ACETYLGLUCOSAMINE
dc.subject	ESCHERICHIA-COLI
dc.subject	VIRULENCE FACTORS
dc.subject	LIPOPOLYSACCHARIDE BIOSYNTHESIS
dc.subject	OPPORTUNISTIC PATHOGEN
dc.subject	CRYSTAL-STRUCTURE
dc.subject	ENDOTOXINS
dc.subject	ANTIBIOTICS
dc.subject.other	Биология
dc.subject.other	Медицина и здравоохранение
dc.title	Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa
dc.type	Article
dc.contributor.org	Институт экологии и природопользования
dc.description.pages
dc.relation.ispartofseries-issue	10
dc.relation.ispartofseries-volume	12
dc.pub-id	167144