Kazan Federal University Digital Repository

Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

Show simple item record

dc.contributor Казанский федеральный университет
dc.contributor.author Elamin Ayssar A.
dc.contributor.author Steinicke Susanne
dc.contributor.author Oehlmann Wulf
dc.contributor.author Braun Yvonne
dc.contributor.author Wanas Hanaa
dc.contributor.author Shuralev Eduard Arkadevich
dc.contributor.author Huck Carmen
dc.contributor.author Maringer Marko
dc.contributor.author Rohde Manfred
dc.contributor.author Singh Mahavir
dc.date.accessioned 2017-11-21T08:54:45Z
dc.date.available 2017-11-21T08:54:45Z
dc.date.issued 2017
dc.identifier.citation Elamin A.A. Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa / A.A. Elamin, S. Steinicke, W. Oehlmann, Y. Braun, H. Wanas, E.A. Shuralev, C. Huck, M. Maringer, M. Rohde, M. Singh // PLoS ONE. - 2017. - 12(10): e0186801. DOI: 10.1371/journal.pone.0186801. WOS:000413168100091
dc.identifier.issn 1932-6203
dc.identifier.uri http://dspace.kpfu.ru/xmlui/handle/net/117107
dc.description.abstract This study demonstrates that cell wall targets contribute significantly to intracellular survival, in vivo growth, and pathogenesis of P. aeruginosa. In conclusion, these findings establish a link between cell wall targets and virulence of P. aeruginosa and thus may lead to development of novel drugs for the treatment of P. aeruginosa infection.
dc.language.iso en
dc.relation.ispartofseries PLos ONE
dc.rights открытый доступ
dc.subject ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE
dc.subject BACTERIAL BIOFILM FORMATION
dc.subject UDP-N-ACETYLGLUCOSAMINE
dc.subject ESCHERICHIA-COLI
dc.subject VIRULENCE FACTORS
dc.subject LIPOPOLYSACCHARIDE BIOSYNTHESIS
dc.subject OPPORTUNISTIC PATHOGEN
dc.subject CRYSTAL-STRUCTURE
dc.subject ENDOTOXINS
dc.subject ANTIBIOTICS
dc.subject.other Биология
dc.subject.other Медицина и здравоохранение
dc.title Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa
dc.type Article
dc.contributor.org Институт экологии и природопользования
dc.description.pages
dc.relation.ispartofseries-issue 10
dc.relation.ispartofseries-volume 12
dc.pub-id 167144


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account