Synthesis, Structure and Biological Activity of
Dicarboxylate Phosphabetaines

Bahtiyarov Dmitrij Ilgizarovich; Galkina Irina Vasilevna; Bakhtiyarova Yuliya Valerevna; Morozov Maksim Vyacheslavovich; Minnullin Rail Radikovich; hIslamov Daut Rinatovich; Galkin Vladimir Ivanovich; Dobrynin Aleksej Borisovich; Cherkasov Rafael Ashatovic; Kataeva Olga Nikolaevna

Synthesis, Structure and Biological Activity of Dicarboxylate Phosphabetaines

Bakhtiyarova Yuliya Valerevna; Minnullin Rail Radikovich; Morozov Maksim Vyacheslavovich; Bahtiyarov Dmitrij Ilgizarovich; hIslamov Daut Rinatovich; Dobrynin Aleksej Borisovich; Kataeva Olga Nikolaevna; Cherkasov Rafael Ashatovic; Galkin Vladimir Ivanovich; Galkina Irina Vasilevna

URI: http://dspace.kpfu.ru/xmlui/handle/net/104327

Дата: 2016

Аннотации:

New stable dicarboxylate phosphabetaines were synthesized by the phosphorylation of a series of unsaturated carboxylic acids. Interaction of 3-(diphenylphosphonio)propionic acid with unsaturated monocarboxylic acids leads to formation of stable dicarboxylate phosphabetaines. The structure of the isolated compounds was determined by IR and NMR spectroscopy, X-ray single crystal diffraction studies and elemental analysis. Their thermal stability was studied by simultaneous thermogravimetry and differential scanning calorimetry. All of the synthesized compounds were tested for their antibacterial and anti-Candida activity.

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