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Просмотр по автору "Tyakht A."

Просмотр по автору "Tyakht A."

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  • Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis 
    Tyakht A.; Dubinkina V.; Odintsova V.; Yarygin K.; Kovarsky B.; Pavlenko A.; Ischenko D.; Popenko A.; Alexeev D.; Taraskina A.; Nasyrova R.; Krupitski E.; Shalikiani N.; Bakulin I.; Shcherbakov P.; Skorodumova L.; Larin A.; Kostryukova E.; Abdulkhakov R.; Abdulkhakov S.; Malanin S.; Ismagilova R.; Grigoryeva T.; Ilina E.; Govorun V. (2017)
    © 2017Alcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We ...
  • Data on gut metagenomes of the patients with Helicobacter pylori infection before and after the antibiotic therapy 
    Glushchenko O.; Samoilov A.; Olekhnovich E.; Kovarsky B.; Tyakht A.; Pavlenko A.; Babenko V.; Larin A.; Kostryukova E.; Malakhova M.; Ilina E.; Abdulkhakov R.; Safina D.; Grigoryeva T.; Abdulkhakov S.; Govorun V. (2017)
    © 2017Antibiotic therapy can lead to the disruption of gut microbiota community with possible negative outcomes for human health. One of the diseases for which the treatment scheme commonly included antibiotic intake is ...
  • Genetic diversity of Escherichia coli in gut microbiota of patients with Crohn's disease discovered using metagenomic and genomic analyses 
    Tyakht A.; Manolov A.; Kanygina A.; Ischenko D.; Kovarsky B.; Popenko A.; Pavlenko A.; Elizarova A.; Rakitina D.; Baikova J.; Ladygina V.; Kostryukova E.; Karpova I.; Semashko T.; Larin A.; Grigoryeva T.; Sinyagina M.; Malanin S.; Shcherbakov P.; Kharitonova A.; Khalif I.; Shapina M.; Maev I.; Andreev D.; Belousova E.; Buzunova Y.; Alexeev D.; Govorun V. (2018)
    © 2018 The Author(s). Background: Crohn's disease is associated with gut dysbiosis. Independent studies have shown an increase in the abundance of certain bacterial species, particularly Escherichia coli with the ...
  • Gut Microbiome Shotgun Sequencing in Assessment of Microbial Community Changes Associated with H. pylori Eradication Therapy 
    Khusnutdinova D.; Grigoryeva T.; Abdulkhakov S.; Safina D.; Siniagina M.; Markelova M.; Boulygina E.; Malanin S.; Tyakht A.; Kovarsky B.; Ismagilova R.; Abdulkhakov R.; Chernov V. (2016)
    © 2016, Springer Science+Business Media New York.Disturbance of intestinal microbiota content and functions often results in different pathological conditions. Pharmacotherapy including antibiotics use is one of the factors ...
  • Gut microbiome signature of Viliuisk encephalomyelitis in Yakuts includes an increase in microbes linked to lean body mass and eating behaviour 
    Kuznetsova V.; Tyakht A.; Akhmadishina L.; Odintsova V.; Klimenko N.; Kostryukova E.; Vakhitova M.; Grigoryeva T.; Malanin S.; Vladimirtsev V.; Nikitina R.; Volok V.; Osakovskiy V.; Sivtseva T.; Platonov F.; Alexeev D.; Karganova G. (2020)
    © 2020, The Author(s). Background: Viliuisk encephalomyelitis (VE) is a rare endemic neurodegenerative disease occurring in the Yakut population of Northeastern Siberia. The main clinical features of VE are spasticity, ...
  • Human gut microbiota community structures in urban and rural populations in Russia 
    Tyakht A.; Kostryukova E.; Popenko A.; Belenikin M.; Pavlenko A.; Larin A.; Karpova I.; Selezneva O.; Semashko T.; Ospanova E.; Babenko V.; Maev I.; Cheremushkin S.; Kucheryavyy Y.; Shcherbakov P.; Grinevich V.; Efimov O.; Sas E.; Abdulkhakov R.; Abdulkhakov S.; Lyalyukova E.; Livzan M.; Vlassov V.; Sagdeev R.; Tsukanov V.; Osipenko M.; Kozlova I.; Tkachev A.; Sergienko V.; Alexeev D.; Govorun V. (2013)
    The microbial community of the human gut has a crucial role in sustaining host homeostasis. High-throughput DNA sequencing has delineated the structural and functional configurations of gut metagenomes in world populations. ...
  • Markers of dysbiosis in patients with ulcerative colitis and Crohn's disease 
    Danilova N.; Abdulkhakov S.; Grigoryeva T.; Markelova M.; Vasilyev I.; Boulygina E.; Ardatskaya M.; Pavlenko A.; Tyakht A.; Odintsova A.; Abdulkhakov R. (2019)
    © 2019 Consilium Medikum. All rights reserved. The results of recent studies indicate a significant role of gut microbiota in the pathogenesis of inflammatory bowel diseases (IBD). The aim of the study was to study the ...
  • Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity 
    Terekhov S.; Smirnov I.; Stepanova A.; Bobik T.; Mokrushina Y.; Ponomarenko N.; Belogurov A.; Rubtsova M.; Kartseva O.; Gomzikova M.; Moskovtsev A.; Bukatin A.; Dubina M.; Kostryukova E.; Babenko V.; Vakhitova M.; Manolov A.; Malakhova M.; Kornienko M.; Tyakht A.; Vanyushkina A.; Ilina E.; Masson P.; Gabibov A.; Altman S. (2017)
    © 2017, National Academy of Sciences. All rights reserved.Ultrahigh-throughput screening (uHTS) techniques can identify unique functionality from millions of variants. To mimic the natural selection mechanisms that occur ...
  • RNA-Seq gene expression profiling of HepG2 cells: The influence of experimental factors and comparison with liver tissue 
    Tyakht A.; Ilina E.; Alexeev D.; Ischenko D.; Gorbachev A.; Semashko T.; Larin A.; Selezneva O.; Kostryukova E.; Karalkin P.; Vakhrushev I.; Kurbatov L.; Archakov A.; Govorun V. (2014)
    © Tyakht et al.; licensee BioMed Central. Background: Human hepatoma HepG2 cells are used as an in vitro model of the human liver. High-throughput transcriptomic sequencing is an advanced approach for assessing the functional ...
  • Shifts in the human gut microbiota structure caused by quadruple helicobacter pylori eradication therapy 
    Olekhnovich E.; Manolov A.; Samoilov A.; Prianichnikov N.; Malakhova M.; Tyakht A.; Pavlenko A.; Babenko V.; Larin A.; Kovarsky B.; Starikova E.; Glushchenko O.; Safina D.; Markelova M.; Boulygina E.; Khusnutdinova D.; Malanin S.; Abdulkhakov S.; Abdulkhakov R.; Grigoryeva T.; Kostryukova E.; Govorun V.; Ilina E. (2019)
    © 2019 Olekhnovich, Manolov, Samoilov, Prianichnikov, Malakhova, Tyakht, Pavlenko, Babenko, Larin, Kovarsky, Starikova, Glushchenko, Safina, Markelova, Boulygina, Khusnutdinova, Malanin, Abdulkhakov, Abdulkhakov, Grigoryeva, ...

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