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A Set of Genetic Constructs for Binase and Barstar Overproduction

Ulyanova V.; Shah Mahmud R.; Klug G.; Preissner K.; Vershinina V.; Ilinskaya O. (2017)

© 2016, Springer Science+Business Media New York.Low molecular weight guanyl-preferring ribonuclease (RNase) secreted by Bacillus pumilus is referred to as binase and regarded as a potential agent to target oncogenic ...
Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells

Unknown author (2018)

© The Author(s). 2018 Background: Influenza is a severe contagious disease especially in children, elderly and immunocompromised patients. Beside vaccination, the discovery of new anti-viral agents represents an important ...
Binase cleaves cellular noncoding RNAs and affects coding mRNAs

Mitkevich V.; Tchurikov N.; Zelenikhin P.; Petrushanko I.; Makarov A.; Ilinskaya O. (2010)

Bacterial RNases are promising tools for the development of anticancer drugs. Neoplastic transformation leads to enhanced accumulation of rRNA and tRNA, and altered expression of regulatory noncoding RNAs. Cleavage of RNA ...
Binase Immobilized on halloysite nanotubes exerts enhanced cytotoxicity toward human colon adenocarcinoma cells

Khodzhaeva V.; Makeeva A.; Ulyanova V.; Zelenikhin P.; Evtugyn V.; Hardt M.; Rozhina E.; Lvov Y.; Fakhrullin R.; Ilinskaya O. (2017)

© 2017 Khodzhaeva, Makeeva, Ulyanova. Many ribonucleases (RNases) are considered as promising tools for antitumor therapy because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus pumilus, ...
Binase-Induced Changes of Tumor Cell Membranes

Unknown author (2018)

© 2018, Allerton Press, Inc. Exogenous ribonucleases of Bacilli can selectively induce apoptosis of malignant cells. The ability of Bacillus pumilus ribonuclease, binase, to induce processes leading to a dynamic disruption ...
Effect of the RNase from bacillus intermedius on growth and physiological characteristics of Escherichia coli

Egorov S.; Ulakhovich S.; Dmitriev V.; Kupriyanova-Ashina F.; Leshchinskaya I. (1999)

The effect of the RNase from Bacillus intermedius on the growth of Escherichia coli was investigated. RNase added to growth medium enhanced the synthesis of DNA, RNA, and protein and stimulated cell division; the degree ...
Preparations of Bacillus pumilus secreted RNase: One enzyme or two?

Ulyanova V.; Khodzhaeva V.; Dudkina E.; Laikov A.; Vershinina V.; Ilinskaya O. (2015)

© 2015, Pleiades Publishing, Ltd. Immunochemical analysis of the following purified preparations of Bacillus pumilus RNase (binase) was carried out: industrially manufactured enzyme (Institute of Organic Synthesis, Riga, ...
РИБОНУКЛЕОЛИТИЧЕСКАЯ АКТИВНОСТЬ БАКТЕРИАЛЬНОЙ МИКРОФЛОРЫ НОРМАЛЬНОГО И МАЛИГНИЗИРОВАННОГО ЭПИТЕЛИЯ ПРЯМОЙ КИШКИ // Ученые записки КФУ. Естественные науки 2013 том155 N3

Нгуен Тхи Нга; Зеленихин Павел Валерьевич; Гатауллин Ильгиз Габдуллович; Ильинская Ольга Николаевна (2013)

В последние десятилетия происходит увеличение частоты возникновения колоректального рака. Среди прочих причин исследователи отмечают, что в развитие злокачественных новообразований данного типа вовлечена микрофлора эпителия ...

Now showing items 1-8 of 8

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Browsing by Subject "RNase"

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