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Browsing by Author "Onoe H."

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Disrupting tumor onset and growth via selective cell tagging (SeCT) therapy

Vong K.; Tahara T.; Urano S.; Nasibullin I.; Tsubokura K.; Nakao Y.; Kurbangalieva A.; Onoe H.; Watanabe Y.; Tanaka K. (2021)

This study presents the early framework of selective cell tagging (SeCT) therapy, which is the concept of preferentially labeling specific cells in vivo with chemical moieties that can elicit a therapeutic response. Using ...
Glycan multivalency effects toward albumin enable N-glycan-dependent tumor targeting

Ogura A.; Tahara T.; Nozaki S.; Onoe H.; Kurbangalieva A.; Watanabe Y.; Tanaka K. (2016)

© 2016 Elsevier Ltd. All rights reserved.Multivalent interactions play an essential role in molecular recognition in living systems. These effects were employed to target tumor cells using albumin clusters bearing ∼10 ...
In Vivo Gold Complex Catalysis within Live Mice

Tsubokura K.; Vong K.; Pradipta A.; Ogura A.; Urano S.; Tahara T.; Nozaki S.; Onoe H.; Nakao Y.; Sibgatullina R.; Kurbangalieva A.; Watanabe Y.; Tanaka K. (2017)

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, WeinheimMetal complex catalysis within biological systems is largely limited to cell and bacterial systems. In this work, a glycoalbumin–AuIII complex was designed and developed ...
In vivo imaging of advanced glycation end products (AGEs) of albumin: First observations of significantly reduced clearance and liver deposition properties in mice

Tsutsui A.; Ogura A.; Tahara T.; Nozaki S.; Urano S.; Hara M.; Kojima S.; Kurbangalieva A.; Onoe H.; Watanabe Y.; Taniguchi N.; Tanaka K. (2016)

© 2016 The Royal Society of Chemistry.Advanced glycation end products (AGEs) are associated with various diseases, especially during aging and the development of diabetes and uremia. To better understand these biological ...
Visualizing Trimming Dependence of Biodistribution and Kinetics with Homo-and Heterogeneous N-Glycoclusters on Fluorescent Albumin

Ogura A.; Tahara T.; Nozaki S.; Morimoto K.; Kizuka Y.; Kitazume S.; Hara M.; Kojima S.; Onoe H.; Kurbangalieva A.; Taniguchi N.; Watanabe Y.; Tanaka K. (2016)

A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo-or heterogeneously clustered efficiently on fluorescent albumin using a method that combined strain-promoted alkyne-azide cyclization ...

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Browsing by Author "Onoe H."

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