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Browsing by Author "Nikitashina A."

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Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS)

Petrov K.; Yagodina L.; Valeeva G.; Lannik N.; Nikitashina A.; Rizvanov A.; Zobov V.; Bukharaeva E.; Reznik V.; Nikolsky E.; Vyskočil F. (2011)

BACKGROUND AND PURPOSE The rat respiratory muscle diaphragm has markedly lower sensitivity than the locomotor muscle extensor digitorum longus (EDL) to the new acetylcholinesterase (AChE) inhibitors, alkylammonium derivatives ...
Macrocyclic derivatives of 6-methyluracil as ligands of the peripheral anionic site of acetylcholinesterase

Semenov V.; Giniyatullin R.; Lushchekina S.; Kots E.; Petrov K.; Nikitashina A.; Minnekhanova O.; Zobov V.; Nikolsky E.; Masson P.; Reznik V. (2014)

© the Partner Organisations 2014. Novel pyrimidinophanes possessing two o-nitrobenzylethyldialkylammonium heads bridging with different spacers were prepared. Pyrimidinophanes 2a, 2b and 3 are reversible inhibitors of ...
Regulation of acetylcholinesterase activity by nitric oxide in rat neuromuscular junction via N-methyl-d-aspartate receptor activation

Petrov K.; Malomouzh A.; Kovyazina I.; Krejci E.; Nikitashina A.; Proskurina S.; Zobov V.; Nikolsky E. (2013)

Acetylcholinesterase (AChE) is an enzyme that hydrolyses the neurotransmitter acetylcholine, thereby limiting spillover and duration of action. This study demonstrates the existence of an endogenous mechanism for the ...
Schwann cells sense and control acetylcholine spillover at the neuromuscular junction by α7 nicotinic receptors and butyrylcholinesterase

Petrov K.; Girard E.; Nikitashina A.; Colasante C.; Bernard V.; Nurullin L.; Leroy J.; Samigullin D.; Colak O.; Nikolsky E.; Plaud B.; Krejci E. (2014)

Terminal Schwann cells (TSCs) are key components of the mammalian neuromuscular junction (NMJ). How the TSCs sense the synaptic activity in physiological conditions remains unclear. We have taken advantage of the distinct ...

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Browsing by Author "Nikitashina A."

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