Home
→
Browsing by Author

Browsing by Author "Nicolas E."

Now showing items 1-8 of 8

Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer

Beck T.; Korobeynikov V.; Kudinov A.; Georgopoulos R.; Solanki N.; Andrews-Hoke M.; Kistner T.; Pépin D.; Donahoe P.; Nicolas E.; Einarson M.; Zhou Y.; Boumber Y.; Proia D.; Serebriiskii I.; Golemis E. (2016)

© 2016 The Author(s)Anti-Müllerian hormone (AMH) and its type II receptor AMHR2, both previously thought to primarily function in gonadal tissue, were unexpectedly identified as potent regulators of transforming growth ...
Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer

Gabitova-Cornell L.; Surumbayeva A.; Peri S.; Franco-Barraza J.; Restifo D.; Weitz N.; Ogier C.; Goldman A.R.; Hartman T.R.; Francescone R.; Tan Y.; Nicolas E.; Shah N.; Handorf E.A.; Cai K.Q.; O'Reilly A.M.; Sloma I.; Chiaverelli R.; Moffitt R.A.; Khazak V.; Fang C.Y.; Golemis E.A.; Cukierman E.; Astsaturov I. (2020)

© 2020 Elsevier Inc. Oncogenic transformation alters lipid metabolism to sustain tumor growth. We define a mechanism by which cholesterol metabolism controls the development and differentiation of pancreatic ductal ...
Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes from a Subset of Patients with Familial Colorectal Carcinomas

Arora S.; Yan H.; Cho I.; Fan H.; Luo B.; Gai X.; Bodian D.; Vockley J.; Zhou Y.; Handorf E.; Egleston B.; Andrake M.; Nicolas E.; Serebriiskii I.; Yen T.; Hall M.; Golemis E.; Enders G. (2015)

© 2015 AGA Institute. Background & Aims DNA structural lesions are prevalent in sporadic colorectal cancer. Therefore, we proposed that gene variants that predispose to DNA double-strand breaks (DSBs) would be found in ...
Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Gaponova A.; Deneka A.; Beck T.; Liu H.; Andrianov G.; Nikonova A.; Nicolas E.; Einarson M.; Golemis E.; Serebriiskii I. (2017)

Ovarian, head and neck, and other cancers are commonly treated with cisplatin and other DNA damaging cytotoxic agents. Altered DNA damage response (DDR) contributes to resistance of these tumors to chemotherapies, some ...
Interaction of germline variants in a family with a history of early-onset clear cell renal cell carcinoma

Nicolas E.; Demidova E.; Iqbal W.; Serebriiskii I.; Vlasenkova R.; Ghatalia P.; Zhou Y.; Rainey K.; Forman A.; Dunbrack R.; Golemis E.; Hall M.; Daly M.; Arora S. (2019)

© 2019 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc. Background: Identification of genetic factors causing predisposition to renal cell carcinoma has helped improve screening, ...
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

Makhov P.; Bychkov I.; Faezov B.; Deneka A.; Kudinov A.; Nicolas E.; Brebion R.; Avril E.; Cai K.Q.; Kharin L.V.; Voloshin M.; Frantsiyants E.; Karnaukhov N.; Kit O.I.; Topchu I.; Fazliyeva R.; Nikonova A.S.; Serebriiskii I.G.; Borghaei H.; Edelman M.; Dulaimi E.; Golemis E.A.; Boumber Y. (2021)

Non-small cell lung cancer (NSCLC) has limited treatment options. Expression of the RNA-binding protein (RBP) Musashi-2 (MSI2) is elevated in a subset of non-small cell lung cancer (NSCLC) tumors upon progression, and ...
Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

Kudinov A.; Deneka A.; Nikonova A.; Beck T.; Ahn Y.; Liu X.; Martinez C.; Schultz F.; Reynolds S.; Yang D.; Cai K.; Yaghmour K.; Baker K.; Egleston B.; Nicolas E.; Chikwem A.; Andrianov G.; Singh S.; Borghaei H.; Serebriiskii I.; Gibbons D.; Kurie J.; Golemis E.; Boumber Y. (2016)

© 2016, National Academy of Sciences. All rights reserved.Non-small cell lung cancer (NSCLC) has a 5-y survival rate of ∼16%, with most deaths associated with uncontrolled metastasis. We screened for stem cell identity-related ...
Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer

Nicolas E.; Arora S.; Zhou Y.; Serebriiskii I.; Andrake M.; Handorf E.; Bodian D.; Vockley J.; Dunbrack R.; Ross E.; Egleston B.; Hall M.; Golemis E.; Giri V.; Daly M. (2015)

Risk assessment for prostate cancer is challenging due to its genetic heterogeneity. In this study, our goal was to develop an operational framework to select and evaluate gene variants that may contribute to familial ...

Now showing items 1-8 of 8

Search DSpace

Advanced Search

Browse

All of Kazan Federal University Digital Repository

Browsing by Author "Nicolas E."

Browsing by Author "Nicolas E."

Search DSpace

Browse

All of Kazan Federal University Digital Repository

My Account