Browsing by Author "Bodian D."

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Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes from a Subset of Patients with Familial Colorectal Carcinomas

Arora S.; Yan H.; Cho I.; Fan H.; Luo B.; Gai X.; Bodian D.; Vockley J.; Zhou Y.; Handorf E.; Egleston B.; Andrake M.; Nicolas E.; Serebriiskii I.; Yen T.; Hall M.; Golemis E.; Enders G. (2015)

© 2015 AGA Institute. Background & Aims DNA structural lesions are prevalent in sporadic colorectal cancer. Therefore, we proposed that gene variants that predispose to DNA double-strand breaks (DSBs) would be found in ...
Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer

Nicolas E.; Arora S.; Zhou Y.; Serebriiskii I.; Andrake M.; Handorf E.; Bodian D.; Vockley J.; Dunbrack R.; Ross E.; Egleston B.; Hall M.; Golemis E.; Giri V.; Daly M. (2015)

Risk assessment for prostate cancer is challenging due to its genetic heterogeneity. In this study, our goal was to develop an operational framework to select and evaluate gene variants that may contribute to familial ...

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