Browsing by Author "Arkhipova S.S."

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Human mesenchymal stem cells overexpressing interleukin 2 can suppress proliferation of neuroblastoma cells in co-culture and activate mononuclear cells in vitro

Chulpanova D.S.; Solovyeva V.V.; James V.; Arkhipova S.S.; Gomzikova M.O.; Garanina E.E.; Akhmetzyanova E.R.; Tazetdinova L.G.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. High-dose recombinant interleukin 2 (IL2) therapy has been shown to be successful in renal cell carcinoma and metastatic melanoma. However, systemic administration ...
The Function of NG2/CSPG4-expressing Cells in the Rat Spinal Cord Injury: An Immunoelectron Microscopy Study

Kabdesh I.M.; Arkhipova S.S.; Mukhamedshina Y.O.; James V.; Rizvanov A.A.; Chelyshev Y.A. (2021)

Emerging evidence supports an increased role for NG2/CSPG4-expressing cells in the process of neuroregeneration and synaptic plasticity, due to the increased production of multifunctional chondroitin sulfate proteoglycan ...
Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

Tezcan G.; Garanina E.E.; Alsaadi M.; Gilazieva Z.E.; Martinova E.V.; Markelova M.I.; Arkhipova S.S.; Hamza S.; McIntyre A.; Rizvanov A.A.; Khaiboullina S.F. (2021)

Introduction: Dysregulation of NLRP3 inflammasome complex formation can promote chronic inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation on tumor progression remains controversial. ...

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