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Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice

Rizvanov A.; Guseva D.; Salafutdinov I.; Kudryashova N.; Bashirov F.; Kiyasov A.; Yalvaç M.; Gazizov I.; Kaligin M.; Sahin F.; Mukhamedyarov M.; Palotás A.; Islamov R. (2011)

Current therapy of a number of neuropsychiatric maladies has only symptomatic modality. Effective treatment of these neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), may benefit from combined ...
Retrogradely transported siRNA silences human mutant SOD1 in spinal cord motor neurons

Rizvanov A.; Mukhamedyarov M.; Palotás A.; Islamov R. (2009)

The transgenic mouse model of familial amyotrophic lateral sclerosis (ALS) expressing human mutant (G93A) copper/zinc superoxide dismutase (SOD1) is an attractive model for studying the therapeutic effects of RNA interference ...
RNA interference and amyotrophic lateral sclerosis

Rizvanov A.; Gulluoglu S.; Yalvaç M.; Palotás A.; Islamov R. (2011)

Amyotrophic lateral sclerosis (ALS) is a debilitating neuro-degenerative disorder characterized by progressive loss of motor neurons. The etiology and molecular pathogenesis of cell death in most sub-types of the disease ...
Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule

Islamov R.; Rizvanov A.; Mukhamedyarov M.; Salafutdinov I.; Garanina E.; Fedotova V.; Solovyeva V.; Mukhamedshina Y.; Safiullov Z.; Izmailov A.; Guseva D.; Zefirov A.; Kiyasov A.; Palotás A. (2015)

© 2015 Bentham Science Publishers. Amyotrophic lateral sclerosis (ALS) is an incurable, chronic, fatal neuro-degenerative disease characterized by progressive loss of moto-neurons and paralysis of skeletal muscles. ...
Tandem Delivery of Multiple Therapeutic Genes Using Umbilical Cord Blood Cells Improves Symptomatic Outcomes in ALS

Islamov R.; Rizvanov A.; Fedotova V.; Izmailov A.; Safiullov Z.; Garanina E.; Salafutdinov I.; Sokolov M.; Mukhamedyarov M.; Palotás A. (2016)

© 2016 Springer Science+Business Media New YorkCurrent treatment options of chronic, progressive degenerative neuropsychiatric conditions offer only marginal efficacy, and there is no therapy which arrests or even reverses ...
Tandem Delivery of Multiple Therapeutic Genes Using Umbilical Cord Blood Cells Improves Symptomatic Outcomes in ALS

Islamov R.; Rizvanov A.; Fedotova V.; Izmailov A.; Safiullov Z.; Garanina E.; Salafutdinov I.; Sokolov M.; Mukhamedyarov M.; Palotás A. (2017)

© 2016, Springer Science+Business Media New York. Current treatment options of chronic, progressive degenerative neuropsychiatric conditions offer only marginal efficacy, and there is no therapy which arrests or even ...

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Просмотр по теме "Amyotrophic lateral sclerosis (ALS)"

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