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Просмотр по автору "Pashirova T."

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Calix[4]resorcinolarenes with alkylphosphonic fragments: Protolytic properties and interaction with lanthanum(III)

Sal'nikov Y.; Boos G.; Ryzhkina I.; Burilov A.; Pashirova T.; Gazizov A. (2006)

The protolytic and complexing properties of phosphorylated derivatives of calix[4]resorcinolarenes were studied by pH-metric titration at 298 K in water-2-propanol (80 vol % 2-propanol). It was shown that calix[4] ...
Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection

Pashirova T.; Braïki A.; Zueva I.; Petrov K.; Babaev V.; Burilova E.; Samarkina D.; Rizvanov I.; Souto E.; Jean L.; Renard P.; Masson P.; Zakharova L.; Sinyashin O. (2018)

© 2018 Elsevier B.V. A novel approach for brain protection against poisoning by organophosphorus agents is developed based on the combination treatment of dual delivery of two oximes. Pralidoxime chloride (2-PAM) and a ...
Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

Zhil'tsova E.; Ibatullina M.; Lukashenko S.; Pashirova T.; Voloshina A.; Zobov V.; Ziganshina S.; Kutyreva M.; Zakharova L. (2016)

© 2016, Springer Science+Business Media New York.The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of ...
Complexes of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with transition metal nitrates. Micelle-forming, solubilizing, and adsorption properties

Zhiltsova E.; Ibatullina M.; Lukashenko S.; Valeeva F.; Pashirova T.; Kutyreva M.; Zakharova L. (2017)

© 2017, Pleiades Publishing, Ltd. Amphiphilic complexes of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide (D-16) with nitrates of transition metals (La 3+ , Cu 2+ , Ni 2+ , and Co 2+ ) have been synthesized and ...
Micellization of alkylated 1.4-diazabicyclo[2.2.2]octane by nuclear magnetic resonance technique using pulsed gradient of static magnetic field

Zakharova L.; Gaysin N.; Gnezdilov O.; Bashirov F.; Kashapov R.; Zhiltsova E.; Pashirova T.; Lukashenko S. (2012)

A phenomenon of micellization of 4-aza-1-tetradecyl-1-azoniabicyclo[2.2.2] octane bromide (AB-14) in aqueous solution has been studied by the methods of nuclear magnetic resonance using magnetic field pulse gradient and ...
Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model

Pashirova T.; Zueva I.; Petrov K.; Lukashenko S.; Nizameev I.; Kulik N.; Voloshina A.; Almasy L.; Kadirov M.; Masson P.; Souto E.; Zakharova L.; Sinyashin O. (2018)

© 2018 Elsevier B.V. New mixed cationic liposomes based on L-α-phosphatidylcholine and dihexadecylmethylhydroxyethylammonium bromide (DHDHAB) were designed to overcome the BBB crossing by using the intranasal route. Synthesis ...
Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity

Pashirova T.; Zueva I.; Petrov K.; Babaev V.; Lukashenko S.; Rizvanov I.; Souto E.; Nikolsky E.; Zakharova L.; Masson P.; Sinyashin O. (2017)

© 2017 American Chemical Society.Solid lipid nanoparticles (SLNs) are among the most promising nanocarriers to target the blood-brain barrier (BBB) for drug delivery to the central nervous system (CNS). Encapsulation of ...
New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease

Zueva I.; Dias J.; Lushchekina S.; Semenov V.; Mukhamedyarov M.; Pashirova T.; Babaev V.; Nachon F.; Petrova N.; Nurullin L.; Zakharova L.; Ilyin V.; Masson P.; Petrov K. (2019)

© 2019 Elsevier Ltd Profound synaptic dysfunction contributes to early loss of short-term memory in Alzheimer's disease. This study was set up to analyze possible neuroprotective effects of two dual binding site inhibitors ...
Synthesis, biological evaluation and structure-activity relationships of self-assembled and solubilization properties of amphiphilic quaternary ammonium derivatives of quinuclidine

Burilova E.; Pashirova T.; Lukashenko S.; Sapunova A.; Voloshina A.; Zhiltsova E.; Campos J.; Souto E.; Zakharova L. (2018)

© 2018 Elsevier B.V. This work deals with development of polyfunctional biocompatible cationic surfactant systems based on bioactive saturated bicyclic alkaloid quinuclidine. It is focused on the effect of the chemical ...

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