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Application of cell and tissue culture systems for anticancer drug screening

Blatt N.; Mingaleeva R.; Khaiboullina S.; Lombardi V.; Rizvanov A. (2013)

A primary reason why potential anticancer drugs fail in clinical trials is the limitations of existing in vitro screening systems. The purpose of in vitro testing is to aid in the selection of efficacious compounds from a ...
Electron Paramagnetic Resonance in the Experimental Oncology: Implementation Examples of the Conventional Approaches

Burlaka A.; Gafurov M.; Iskhakova K.; Lukin S.; Rodionov A.; Sidorik E.; Vovk A. (2016)

© 2016, Springer Science+Business Media New York.This paper presents a mini-review of application of electron paramagnetic resonance (EPR) in the experimental oncology studies based on the authors’ experience acquired at ...
In vitro and in vivo cancer cell apoptosis triggered by competitive binding of Cinchona alkaloids to the RING domain of TRAF6

Qi Y.; Zhao X.; Chen J.; Pradipta A.; Wei J.; Ruan H.; Zhou L.; Hsung R.; Tanaka K. (2019)

© 2018 Japan Society for Bioscience, Biotechnology, and Agrochemistry TRAF6 is highly expressed in many tumors and plays an important role in the immune system. The aim of this study is to confirm anti-tumor activities of ...
In vivo screening models of anticancer drugs

Blatt N.; Mingaleeva R.; Khaiboullina S.; Kotlyar A.; Lombardi V.; Rizvanov A. (2013)

Animal models have been indispensable when conducting research to further the understanding of cancer biology and when developing anticancer drugs. This article presents an overview of the most commonly utilized animal ...

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Browsing by Subject "Tumor"

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