Browsing by Author "Vorobiev I."

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Chemical polysialylation of recombinant human proteins

Smirnov I.; Vorobiev I.; Belogurov A.; Genkin D.; Deyev S.; Gabibov A. (2015)

© Springer Science+Business Media New York 2015. All right reserved. Design of drug with prolonged therapeutic action is one of the rapid developing fields of modern medical science and required implementation of different ...
Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells

Orlova N.; Kovnir S.; Hodak J.; Vorobiev I.; Gabibov A.; Skryabin K. (2014)

Background: Establishing highly productive clonal cell lines with constant productivity over 2-3 months of continuous culture remains a tedious task requiring the screening of tens of thousands of clonal colonies. In ...
Peculiarities of the Mechanism of Interactions of Catalytic Antibodies with Organophosphorus Substrates

Mokrushina Y.; Pipiya S.; Stepanova A.; Shamborant O.; Knorre V.; Smirnov I.; Gabibov A.; Vorobiev I. (2017)

© 2017, Pleiades Publishing, Inc. Catalytic antibodies are a promising model for creating highly specific biocatalysts with predetermined activity. However, in order to realize the directed change or improve their properties, ...

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