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Browsing by Author "Hussain I."

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Biological Evaluation of Newly Synthesized Biaryl Guanidine Derivatives to Arrest β -Secretase Enzymatic Activity Involved in Alzheimer's Disease

Ali S.; Asad M.H.H.B.; Khan F.; Murtaza G.; Rizvanov A.A.; Iqbal J.; Babak B.; Hussain I. (2020)

© 2020 Sayyad Ali et al. Proteases BACE1 (β-secretases) enzymes have been recognized as a promising target associated with Alzheimer's disease (AD). This study was carried out on the principles of molecular docking, chemical ...
Effect of varying quantities of polymer on preparation and stability evaluation of carbamazepine cocrystals with dicarboxylic acid coformers

Wasim M.; Mannan A.; Ullah K.; Yameen M.A.; Latif M.; Ahmad T.; Ullah M.; Amirzada M.I.; Khan H.U.; Maheen S.; Khan S.A.; Jamil Q.A.; Hassan Bin Asad M.H.; Hussain I. (2020)

© 2020 Pakistan Journal of Pharmaceutical Sciences. All rights reserved. The current study is an attempt to explore the effect of varying quantities of hydroxypropyl cellulose (HPC) polymer on carbamazepine (CBZ) cocrystal ...
Erupt of malaria, dengue and chikungunya in Pakistan: Recent insights about prevalence, diagnosis and treatment

Hassan Bin Asad M.; Nazir H.; Khalid S.; Bibi S.; Afzal K.; Al-Kharaman Y.; Ali A.; Ali S.; Shah H.; Khan M.; Akhtar Hussain S.; Farid Hasan S.; Hussain I.; Rizvanov A. (2019)

© 2019 Pakistan Journal of Pharmaceutical Sciences. All rights reserved. Malaria, dengue and chikungunya are the most rampant mosquito-borne infections predominantly in Pakistan. They pose a serious threat and cause a havoc ...
Fabrication of Carbamazepine Cocrystals: Characterization, in Vitro and Comparative in Vivo Evaluation

Wasim M.; Mannan A.; Asad M.H.H.B.; Amirzada M.I.; Shafique M.; Hussain I. (2021)

Carbamazepine (CBZ) is an antiepileptic drug having low bioavailability due to its hydrophobic nature. In the current study, efforts are made to investigate the effect of dicarboxylic acid coformer spacer groups (aliphatic ...
Fluoro-benzimidazole derivatives to cure Alzheimer's disease: In-silico studies, synthesis, structure-activity relationship and in vivo evaluation for β secretase enzyme inhibition

Ali S.; Asad M.; Maity S.; Zada W.; Rizvanov A.; Iqbal J.; Babak B.; Hussain I. (2019)

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Browsing by Author "Hussain I."

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