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Spinal segment-specific transcutaneous stimulation differentially shapes activation pattern among motor pools in humans

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dc.contributor.author Sayenko D.
dc.contributor.author Atkinson D.
dc.contributor.author Dy C.
dc.contributor.author Gurley K.
dc.contributor.author Smith V.
dc.contributor.author Angeli C.
dc.contributor.author Harkema S.
dc.contributor.author Edgerton V.
dc.contributor.author Gerasimenko Y.
dc.date.accessioned 2018-09-18T20:49:06Z
dc.date.available 2018-09-18T20:49:06Z
dc.date.issued 2015
dc.identifier.issn 8750-7587
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/142474
dc.description.abstract Copyright © 2015 the American Physiological Society. Transcutaneous and epidural electrical spinal cord stimulation techniques are becoming more valuable as electrophysiological and clinical tools. Recently, we observed selective activation of proximal and distal motor pools during epidural spinal stimulation. In the present study, we hypothesized that the characteristics of recruitment curves obtained from leg muscles will reflect a relative preferential activation of proximal and distal motor pools based on their arrangement along the lumbosacral enlargement. The purpose was to describe the electrophysiological responses to transcutaneous stimulation in leg muscles innervated by motoneurons from different segmental levels. Stimulation delivered along the rostrocaudal axis of the lumbosacral enlargement in the supine position resulted in a selective topographical recruitment of proximal and distal leg muscles, as described by threshold intensity, slope of the recruitment curves, and plateau point intensity and magnitude. Relatively selective recruitment of proximal and distal motor pools can be titrated by optimizing the site and intensity level of stimulation to excite a given combination of motor pools. The slope of the recruitment of particular muscles allows characterization of the properties of afferents projecting to specific motoneuron pools, as well as to the type and size of the motoneurons. The location and intensity of transcutaneous spinal electrical stimulation are critical to target particular neural structures across different motor pools in investigation of specific neuromodulatory effects. Finally, the asymmetry in bilateral evoked potentials is inevitable and can be attributed to both anatomical and functional peculiarities of individual muscles or muscle groups.
dc.relation.ispartofseries Journal of Applied Physiology
dc.subject Electrophysiological assessment
dc.subject Evoked potentials
dc.subject Human
dc.subject Neurorehabilitation
dc.subject Transcutaneous spinal cord stimulation
dc.title Spinal segment-specific transcutaneous stimulation differentially shapes activation pattern among motor pools in humans
dc.type Article
dc.relation.ispartofseries-issue 11
dc.relation.ispartofseries-volume 118
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 1364
dc.source.id SCOPUS87507587-2015-118-11-SID84932185364


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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