Polyphenothiazine modified electrochemical aptasensor for detection of human α-thrombin

dc.contributor.author	Porfirieva A.
dc.contributor.author	Evtugyn G.
dc.contributor.author	Hianik T.
dc.date.accessioned	2018-09-18T20:13:14Z
dc.date.available	2018-09-18T20:13:14Z
dc.date.issued	2007
dc.identifier.issn	1040-0397
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/137694
dc.description.abstract	QCM aptasensor for detection human thrombin has been developed on the base of polymeric forms of phenothiazine dyes, Methylene Blue and Methylene Green. Electrostatic accumulation of the analyte in the polyphenothiazine layer made it possible to increase the sensitivity of QCM detection of thrombin in comparison with bare gold electrodes coated with avidin or neutravidin. The influence of nonspecific binding of human serum albumin and the optimal composition of the surface layers were determined. The aptasensors developed make it possible to detect 10-100 nM of thrombin. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
dc.relation.ispartofseries	Electroanalysis
dc.subject	DNA aptamer
dc.subject	Methylene blue
dc.subject	Methylene green
dc.subject	QCM
dc.subject	Thrombin
dc.title	Polyphenothiazine modified electrochemical aptasensor for detection of human α-thrombin
dc.type	Article
dc.relation.ispartofseries-issue	18
dc.relation.ispartofseries-volume	19
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	1915
dc.source.id	SCOPUS10400397-2007-19-18-SID34748847598

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.