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Structure of the capsular polysaccharide of Acinetobacter baumannii 1053 having the KL91 capsule biosynthesis gene locus

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dc.contributor.author Shashkov A.
dc.contributor.author Shneider M.
dc.contributor.author Senchenkova S.
dc.contributor.author Popova A.
dc.contributor.author Nikitina A.
dc.contributor.author Babenko V.
dc.contributor.author Kostryukova E.
dc.contributor.author Miroshnikov K.
dc.contributor.author Volozhantsev N.
dc.contributor.author Knirel Y.
dc.date.accessioned 2018-09-18T20:02:31Z
dc.date.available 2018-09-18T20:02:31Z
dc.date.issued 2015
dc.identifier.issn 0008-6215
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/135997
dc.description.abstract © 2014 Elsevier Ltd. All rights reserved. Acinetobacter baumannii 1053 is the type strain for the maintenance of specific bacteriophage AP22, which infects a fairly broad range of A. baumannii strains circulating in Russian clinics and hospitals. A capsular polysaccharide (CPS) was isolated from cells of strain 1053 and studied by sugar analysis along with 1D and 2D 1H and 13C NMR spectroscopy. The following structure of the linear trisaccharide repeating unit was established: →4)-β-D-ManpNAcA-(1→4)-β-D-ManpNAcA-(1→3)-α-D-FucpNAc-(1→ where ManNAcA and FucNAc indicate 2-acetamido-2-deoxymannuronic acid and 2-acetamido-2,6-dideoxygalactose, respectively. A polysaccharide having the same repeating unit but a shorter chain was isolated by the phenol-water extraction of bacterial cells. Sequencing of the CPS biosynthesis gene locus showed that A. baumannii 1053 belongs to a new group designated KL91. The gene functions assigned putatively by a comparison with available databases were in agreement with the CPS structure established.
dc.relation.ispartofseries Carbohydrate Research
dc.subject 2-Acetamido-2 6-dideoxy-d-galactose
dc.subject 2-Acetamido-2-deoxy-d-mannuronic acid
dc.subject Acinetobacter baumannii
dc.subject Capsular polysaccharide structure
dc.subject Polysaccharide biosynthesis gene locus
dc.title Structure of the capsular polysaccharide of Acinetobacter baumannii 1053 having the KL91 capsule biosynthesis gene locus
dc.type Article
dc.relation.ispartofseries-volume 404
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 79
dc.source.id SCOPUS00086215-2015-404-SID84922361375


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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